Evidence map›Paper›PMID 36323677›Full record

ArticleNature communications2022

Deep learning empowered volume delineation of whole-body organs-at-risk for accelerated radiotherapy.

Feng Shi, Weigang Hu, Jiaojiao Wu, Miaofei Han, Jiazhou Wang, Wei Zhang, Qing Zhou, Jingjie Zhou, Ying Wei, Ying Shao and 7 more

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed.

  1. Article
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  5. Radiation oncology at a new frontier: Hotspots, challenges, and emerging advances.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2026
    Article
  6. Article
  7. Article
  8. HAR-Net: Automatic delineation of clinical target volumes for cervical cancer guided by hierarchical anatomical refinement.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Article
  9. Article
  10. Article
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  13. Article
  14. Article
  15. Review
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  17. Observational
  18. Article
  19. Educational Impact of a National Training Webinar on AI-based Automatic Contouring in Radiation Oncology.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Feng Shi *Department of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Weigang Hu *Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Jiaojiao Wu *Department of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Miaofei HanDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Jiazhou WangDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.ORCID 0000-0002-9012-6605
Wei ZhangRadiotherapy Business Unit, Shanghai United Imaging Healthcare Co., Ltd., Shanghai, China.
Qing ZhouDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Jingjie ZhouRadiotherapy Business Unit, Shanghai United Imaging Healthcare Co., Ltd., Shanghai, China.
Ying WeiDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Ying ShaoDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Yanbo ChenDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Yue YuDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Xiaohuan CaoDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Yiqiang ZhanDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Xiang Sean ZhouDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Yaozong GaoDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China. yaozong.gao@uii-ai.com.
Dinggang ShenDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China. Dingang.Shen@gmail.com.ORCID 0000-0002-7934-5698

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In radiotherapy for cancer patients, an indispensable process is to delineate organs-at-risk (OARs) and tumors. However, it is the most time-consuming step as manual delineation is always required from radiation oncologists. Herein, we propose a lightweight deep learning framework for radiotherapy treatment planning (RTP), named RTP-Net, to promote an automatic, rapid, and precise initialization of whole-body OARs and tumors. Briefly, the framework implements a cascade coarse-to-fine segmentation, with adaptive module for both small and large organs, and attention mechanisms for organs and boundaries. Our experiments show three merits: 1) Extensively evaluates on 67 delineation tasks on a large-scale dataset of 28,581 cases; 2) Demonstrates comparable or superior accuracy with an average Dice of 0.95; 3) Achieves near real-time delineation in most tasks with <2 s. This framework could be utilized to accelerate the contouring process in the All-in-One radiotherapy scheme, and thus greatly shorten the turnaround time of patients.

Indexed as

Deep LearningNeoplasmsHumansImage Processing, Computer-AssistedOrgans at RiskTomography, X-Ray Computed

Identifiers

PMID36323677
PMCPMC9630370

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.