Evidence map›Paper›PMID 36323469›Full record

ArticleBMJ open2022

Life after COVID-19: the road from intensive care back to living - a prospective cohort study.

Carolina M H Wiertz, Bena Hemmen, Simone J S Sep, Susanne van Santen, Yvette Y van Horn, Sander M J van Kuijk, Jeanine A Verbunt

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Recovery of lung function during the first year after COVID-19: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Language Barriers and Other Determinants of Post-Intensive Care Unit Follow-Up: A 5-Year Review.Mayo Clinic proceedings. Innovations, quality & outcomes · 2026
    Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Health Status and COVID-19 Epidemiology in an Inland Region of Portugal: A Retrospective Study.International journal of environmental research and public health · 2024
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Carolina M H WiertzRehabilitation Medicine, Adelante, Hoensbroek, The Netherlands c.wiertz@adelante-zorggroep.nl.ORCID 0000-0002-7703-2508
Bena HemmenRehabilitation Medicine, Adelante, Hoensbroek, The Netherlands.
Simone J S SepRehabilitation Medicine, Adelante, Hoensbroek, The Netherlands.
Susanne van SantenDepartment of Intensice Care, Maastricht Universitair Medisch Centrum+, Maastricht, The Netherlands.
Yvette Y van HornRehabilitation Medicine, Adelante, Hoensbroek, The Netherlands.
Sander M J van KuijkClinical Epidemiology and Medical Technology Assessment, Maastricht Universitair Medisch Centrum+, Maastricht, The Netherlands.ORCID 0000-0003-2796-729X
Jeanine A VerbuntRehabilitation Medicine, Adelante, Hoensbroek, The Netherlands.
Maastricht University · NLMaastricht University Medical Centre · NLAdelante · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of the study was to evaluate recovery of participation in post-COVID-19 patients during the first year after intensive care unit (ICU) discharge. The secondary aim was to identify the early determinants associated with recovery of participation.

designProspective cohort study.

settingCOVID-19 post-ICU inpatient rehabilitation in the Netherlands, during the first epidemic wave between April and July 2020, with 1-year follow-up.

participantsCOVID-19 ICU survivors ≥18 years of age needing inpatient rehabilitation.

main outcome measuresParticipation in society was assessed by the 'Utrecht Scale for Evaluation of Rehabilitation-Participation' (USER-P) restrictions scale. Secondary measures of body function impairments (muscle force, pulmonary function, fatigue (Multidimensional Fatigue Inventory), breathlessness (Medical Research Council (MRC) breathlessness scale), pain (Numerical Rating Scale)), activity limitations (6-minute walking test, Patient reported outcomes measurement information system (PROMIS) 8b), personal factors (coping (Utrecht Proactive Coping Scale), anxiety and depression (Hospital Anxiety and Depression Scale), post-traumatic stress (Global Psychotrauma Screen-Post Traumatic Stress Disorder), cognitive functioning (Checklist for Cognitive Consequences after an ICU-admission)) and social factors were used. STATISTICAL ANALYSES: linear mixed-effects model, with recovery of participation levels as dependent variable. Patient characteristics in domains of body function, activity limitations, personal and social factors were added as independent variables.

resultsThis study included 67 COVID-19 ICU survivors (mean age 62 years, 78% male). Mean USER-P restrictions scores increased over time; mean participation levels increasing from 62.0, 76.5 to 86.1 at 1, 3 and 12 months, respectively. After 1 year, 50% had not fully resumed work and restrictions were reported in physical exercise (51%), household duties (46%) and leisure activities (29%). Self-reported complaints of breathlessness and fatigue, more perceived limitations in daily life, as well as personal factors (less proactive coping style and anxiety/depression complaints) were associated with delayed recovery of participation (all p value <0.05).

conclusionsThis study supports the view that an integral vision of health is important when looking at the long-term consequence of post-ICU COVID-19. Personal factors such as having a less proactive coping style or mental impairments early on contribute to delayed recovery.

Indexed as

COVID-19Critical CareDyspneaFatigueFemaleHumansIntensive Care UnitsMaleMiddle AgedProspective StudiesQuality of LifeAdult intensive & critical careCOVID-19REHABILITATION MEDICINE

Identifiers

PMID36323469
PMCPMC9638746
OpenAlexW4307925854

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.