ReviewEuropean respiratory review : an official journal of the European Respiratory Society2022
Clinical significance of the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in acute exacerbations of COPD: present and future.
Review in European respiratory review : an official journal of the European Respiratory Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
88 citing papers in PubMed, 3 syntheses or guidelines pooled it, 133 citations in OpenAlex.
- The safety and efficacy of non-typeable Haemophilus influenzae and Moraxella catarrhalis vaccine in chronic obstructive pulmonary disease: a systematic review and meta-analysis of randomized controlled trials.Frontiers in medicine · 2025Pooled it
- Risk factors for Pseudomonas aeruginosa isolation in chronic obstructive pulmonary disease: a systematic review and meta-analysis.BMC pulmonary medicine · 2024Pooled it
- The Diagnostic Value of the Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Deep Venous Thrombosis: A Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisPooled it
- Association between the endothelial activation and stress index and 28-day all-cause mortality in critically ill patients with chronic obstructive pulmonary disease: a retrospective cohort study and predictive model establishment based on machine learning.BMC pulmonary medicine · 2026Article
- One Index Does Not Predict All-Hematological Derived Indices Have Different Predictive Value for ICU Mortality in Critically Ill Patients with Non-Infectious Versus Infectious Acute Exacerbation of COPD.Medicina (Kaunas, Lithuania) · 2026Observational
- Blood cell ratio biomarkers of systemic inflammation in chronic obstructive pulmonary disease.Respiratory research · 2026Article
- Ultrasonographic diaphragmatic assessment as an emergency mortality predictor in acute exacerbation of COPD.International journal of emergency medicine · 2026Article
- Blood Cell Ratio Biomarkers of Non-type 2 Inflammation in Chronic Obstructive Pulmonary.Research square · 2026Article
- Chronic Obstructive Pulmonary Disease and Pulmonary Hypertension: A Comparative Study of Biomarkers and Clinical Indicators.Pulmonary circulation · 2026Article
- Improved prediction value of the CURB-65 score combined with the platelet-to-lymphocyte ratio for mortality in emergency department patients with severe community-acquired pneumonia.Frontiers in medicine · 2026Article
- The Role of Advanced Lung Cancer Inflammation Index in Predicting COPD Exacerbation Risks.International journal of chronic obstructive pulmonary disease · 2026Article
- Dynamic changes of immune cells and therapeutic responses in experimental models of COPD.Frontiers in immunology · 2026Review
- LILRB1 Modulates Neutrophil Migration, NETosis, and Inflammation in Drug-ResistantInfection and drug resistance · 2026Article
- Development and External Validation of a Machine Learning Model for 90-Day Readmission in Hospitalized Older Patients with AECOPD: A Two-Center Study.International journal of chronic obstructive pulmonary disease · 2026Article
- Integrating Machine Learning for Early COPD Prediction in Lung Cancer Patients: A Focus on Systemic Coagulation-Inflammation Index.International journal of chronic obstructive pulmonary disease · 2026Article
- Association of co-exposure to extreme cold and nitrogen dioxide with psoriasis outpatient visits and systemic inflammation.Frontiers in public health · 2026Article
- The Prognostic Significance of Advanced Lung Cancer Inflammation Index in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease Using Noninvasive Ventilatory Support.Canadian respiratory journal · 2026Article
- Association between platelet-to-lymphocyte ratio and 28-day all-cause mortality in patients with asymptomatic coronary artery disease: a cohort study.European journal of medical research · 2025Article
- Association between high-density lipoprotein cholesterol-related inflammation indices and chronic obstructive pulmonary disease: a cross-sectional study employing machine learning analysis.Lipids in health and disease · 2025Article
- Role of Systemic Inflammatory Markers in the Differential Diagnosis of Organizing Pneumonia and Lung Cancer.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are a leading cause of hospitalisation and death in COPD patients. In addition to the identification of better strategies to prevent AECOPD, there is an intense focus on discovering novel markers of disease severity that enhance risk stratification on hospital admission for the targeted institution of aggressive
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.