Evidence map›Paper›PMID 36323229›Full record

ArticleCell metabolism2022

Out of destruction comes new growth: Pore-forming antimicrobials make pancreas grow.

Rebecca Yunker, Maryam Bonakdar, Shipra Vaishnava

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rebecca YunkerMolecular Microbiology and Immunology Department, Brown University, Providence, RI 02192, USA.
Maryam BonakdarMolecular Microbiology and Immunology Department, Brown University, Providence, RI 02192, USA.
Shipra VaishnavaMolecular Microbiology and Immunology Department, Brown University, Providence, RI 02192, USA. Electronic address: shipra_vaishnava@brown.edu.
Brown University · US

Funding

Predoctoral Training Program in Biological Data Science at Brown UniversityT32GM128596 · NIGMS · BROWN UNIVERSITY · PI RAMACHANDRAN, SOHINI, SANDSTEDE, BJORN · 2018 to 2022
$1.5M
NIGMS NIH HHS T32 GM128596
6 · The paper itself

Abstract

Gut-residing bacteria are known to regulate the physiologies of distal organs. However, the mechanism behind the long-distance communication between gut microbes and distal organs remains unknown. In this issue of Cell Metabolism, two studies show that β cell expansion in the pancreas depends on bacterially induced antimicrobials produced in the gut.

Indexed as

Anti-Infective AgentsBacteriaPancreasAnti-Infective Agents

Identifiers

PMID36323229
OpenAlexW4308158351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.