Evidence map›Paper›PMID 36322762›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Control of resistance against bacteriophage killing by a metabolic regulator in meningitis-associated

James P R Connolly, Natasha C A Turner, Ester Serrano, Patricia T Rimbi, Douglas F Browning, Nicky O'Boyle, Andrew J Roe

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Catabolism of serine enantiomers represses enterohemorrhagicProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. NeuO-mediated O-acetylation of uropathogenicJournal of bacteriology · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

James P R ConnollyNewcastle University Biosciences Institute, Newcastle University, Newcastle-upon-Tyne, NE2 4HH, United Kingdom.ORCID 0000-0002-0394-3413
Natasha C A TurnerInstitute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, G12 8TA, United Kingdom.ORCID 0000-0002-2740-6639
Ester SerranoInstitute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, G12 8TA, United Kingdom.
Patricia T RimbiInstitute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, G12 8TA, United Kingdom.ORCID 0000-0002-8880-3638
Douglas F BrowningCollege of Health & Life Sciences, Aston University, Birmingham, B4 7ET, United Kingdom.ORCID 0000-0003-4672-3514
Nicky O'BoyleSchool of Microbiology, University College Cork, National University of Ireland, Cork, T12 K8AF, Ireland.
Andrew J RoeInstitute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, G12 8TA, United Kingdom.ORCID 0000-0003-3698-6134
University of Glasgow · GBAston University · GBNational University of Ireland · IENewcastle University · GB

Funding

UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/R006539/1
6 · The paper itself

Abstract

Ecologically beneficial traits in bacteria are encoded by intrinsic and horizontally acquired genes. However, such traits are not universal, and the highly mosaic nature of bacterial genomes requires control at the transcriptional level to drive these processes. It has emerged that regulatory flexibility is widespread in the

Indexed as

BacteriophagesEscherichia coli ProteinsEndothelial CellsEscherichia coliHumansInfant, NewbornSerineEscherichia coli ProteinsSerinebacteriophagecapsuleE. coliregulationtranscription factor

Identifiers

PMID36322762
PMCPMC9659370
OpenAlexW4308146087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.