Evidence map›Paper›PMID 36322759›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Omics analyses of a somatic

Xiaojie Yu, Yun Zhang, Shunbin Xiong, Joy M McDaniel, Chang Sun, Gilda P Chau, Jovanka Gencel-Augusto, Dhruv Chachad, Rhiannon L Morrissey, Xiayu Rao and 2 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Mutant p53Molecular oncology · 2026
    Article
  2. The Dynamic Alliance of p53 and Metabolism in the Tumor Microenvironment Shapes Tumor Evolution.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  3. Article
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  13. Omics analyses of a somaticProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaojie YuDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Yun ZhangDepartment of Pharmaceutical Sciences, Joan M. Lafleur College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004.
Shunbin XiongDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Joy M McDanielDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Chang SunDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Gilda P ChauDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Jovanka Gencel-AugustoDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Dhruv ChachadDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Rhiannon L MorrisseyDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Xiayu RaoDepartment of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Jing WangDepartment of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Guillermina LozanoDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.ORCID 0000-0001-8985-4886

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Role of p53 Missense Mutations on Tumorigenesis in VivoR01CA082577 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LOZANO, GUILLERMINA · 1999 to 2024
$7.3M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA082577
6 · The paper itself

Abstract

Alterations of the tumor suppressor

Indexed as

Breast NeoplasmsPhosphatidylinositol 3-KinasesAnimalsFemaleHumansMiceProto-Oncogene Proteins c-aktSignal TransductionTOR Serine-Threonine KinasesTumor Suppressor Protein p53MTOR protein, humanPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesTumor Suppressor Protein p53breast cancergenomicsp53Pip5k1c

Identifiers

PMID36322759
PMCPMC9659373

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.