Evidence map›Paper›PMID 36322730›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

An unexpected role for leucyl aminopeptidase in UV tolerance revealed by a genome-wide fitness assessment in a model cyanobacterium.

Elliot L Weiss, Mingxu Fang, Arnaud Taton, Richard Szubin, Bernhard Ø Palsson, B Greg Mitchell, Susan S Golden

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Genotype-phenotype modeling of light ecotypes inbioRxiv : the preprint server for biology · 2026
    Article
  2. Machine learning reveals the transcriptional regulatory network and circadian dynamics ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elliot L WeissIntegrative Oceanography Division, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA 92093.
Mingxu FangCenter for Circadian Biology, University of California San Diego, La Jolla, CA 92093.
Arnaud TatonDepartment of Molecular Biology, University of California San Diego, La Jolla, CA 92093.
Richard SzubinBioengineering Department, University of California San Diego, La Jolla, CA 92093.
Bernhard Ø PalssonBioengineering Department, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0003-2357-6785
B Greg MitchellIntegrative Oceanography Division, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA 92093.
Susan S GoldenDepartment of Molecular Biology, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0002-4264-7019
University of California San Diego · USScripps Institution of Oceanography · US

Funding

Undergraduate Summer Research Experience: Molecular and cellular mechanisms of circadian timekeeping in a prokaryote modelR35GM118290 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOLDEN, SUSAN S · 2016 to 2025
$6.7M
NIGMS NIH HHS R35 GM118290
6 · The paper itself

Abstract

UV radiation (UVR) has significant physiological effects on organisms living at or near the Earth's surface, yet the full suite of genes required for fitness of a photosynthetic organism in a UVR-rich environment remains unknown. This study reports a genome-wide fitness assessment of the genes that affect UVR tolerance under environmentally relevant UVR dosages in the model cyanobacterium

Indexed as

Leucyl AminopeptidaseUltraviolet RaysDNA RepairGlutathionePhotosynthesisGlutathioneLeucyl Aminopeptidasecyanobacteriafitnessleucyl aminopeptidaseRB-TnSeqUV radiation

Identifiers

PMID36322730
PMCPMC9659335
OpenAlexW4308145922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.