Evidence map›Paper›PMID 36322514›Full record

ArticleProceedings. Biological sciences2022

Genomic evidence for ancient human migration routes along South America's Atlantic coast.

Andre Luiz Campelo Dos Santos, Amanda Owings, Henry Socrates Lavalle Sullasi, Omer Gokcumen, Michael DeGiorgio, John Lindo

Abstract readHistorical Article
In one paragraph

Article in Proceedings. Biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Review
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  9. Human N-acetyltransferase 2 (Frontiers in pharmacology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andre Luiz Campelo Dos SantosDepartment of Electrical Engineering and Computer Science, Florida Atlantic University, Boca Raton, FL 33431, USA.
Amanda OwingsDepartment of Anthropology, Emory University, Atlanta, GA 30322, USA.
Henry Socrates Lavalle SullasiDepartment of Archaeology, Federal University of Pernambuco, Recife, Pernambuco 50670-901, Brazil.
Omer GokcumenDepartment of Biological Sciences, State University of New York at Buffalo, Buffalo, NY 14260, USA.
Michael DeGiorgioDepartment of Electrical Engineering and Computer Science, Florida Atlantic University, Boca Raton, FL 33431, USA.
John LindoDepartment of Anthropology, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0002-2533-8505

Funding

Identifying complex modes of adaptation from population-genomic dataR35GM128590 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI Michael DeGiorgio · 2018 to 2026
$2.8M
NIGMS NIH HHS R35 GM128590
6 · The paper itself

Abstract

An increasing body of archaeological and genomic evidence has hinted at a complex settlement process of the Americas by humans. This is especially true for South America, where unexpected ancestral signals have raised perplexing scenarios for the early migrations into different regions of the continent. Here, we present ancient human genomes from the archaeologically rich Northeast Brazil and compare them to ancient and present-day genomic data. We find a distinct relationship between ancient genomes from Northeast Brazil, Lagoa Santa, Uruguay and Panama, representing evidence for ancient migration routes along South America's Atlantic coast. To further add to the existing complexity, we also detect greater Denisovan than Neanderthal ancestry in ancient Uruguay and Panama individuals. Moreover, we find a strong Australasian signal in an ancient genome from Panama. This work sheds light on the deep demographic history of eastern South America and presents a starting point for future fine-scale investigations on the regional level.

Indexed as

Human MigrationNeanderthalsAnimalsBrazilGenome, HumanGenomicsHistory, AncientHumansancient migrationsarchaeogenomicsNortheast Brazilsettlement of the Americas

Identifiers

PMID36322514
PMCPMC9629774

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.