Evidence map›Paper›PMID 36322296›Full record

ReviewReviews in endocrine & metabolic disorders2023

Patient and health care provider knowledge of diabetes and diabetic microvascular complications: a comprehensive literature review.

Melissa A Elafros, Brian C Callaghan, Lesli E Skolarus, Loretta Vileikyte, John G Lawrenson, Eva L Feldman

Abstract readReview
In one paragraph

Review in Reviews in endocrine & metabolic disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Diabetic foot attack: Managing severe sepsis in the diabetic patient.World journal of critical care medicine · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Role of LncRNA MIAT in Diabetic Complications.Current medicinal chemistry · 2024
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Melissa A ElafrosDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-4511-201X
Brian C CallaghanDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-8885-6748
Lesli E SkolarusDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-3088-9838
Loretta VileikyteDivision of Diabetes, Endocrinology, and Gastroenterology, University of Manchester, Manchester, UK.ORCID 0000-0001-8514-2128
John G LawrensonSchool of Health and Psychological Sciences, City, University of London, London, UK.ORCID 0000-0002-2031-6390
Eva L FeldmanDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA. efeldman@umich.edu.ORCID 0000-0002-9162-2694

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WILLIAM H HERMAN · 2013 to 2026
$24.3M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Kanakadurga Singer · 2010 to 2026
$20.3M
Integrated Systems Biology Approach to Diabetic Microvascular ComplicationsR24DK082841 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ABCOUWER, STEVEN F, BROSIUS, FRANK C · 2008 to 2020
$13.1M
Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
Schwann Cell Senescence and the Secretome Provide a Unifying Mechanism for the Onset and Progression of Diabetic NeuropathyR01DK130913 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Eva Lucille Feldman, Junguk Hur · 2022 to 2026
$3.3M
Reach Out: Randomized Clinical Trial of Emergency Department-Initiated Hypertension Behavioral Intervention Connecting Multiple Health SystemsR01MD011516 · NIMHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MEURER, WILLIAM JOSEPH, SKOLARUS, LESLI ELIZABETH · 2017 to 2020
$3.3M
The Effect of High Intensity Interval Training and Surgical Weight Loss On Distal Symmetric Polyneuropathy OutcomesR01DK115687 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CALLAGHAN, BRIAN CHRISTOPHER · 2018 to 2022
$3.1M
Understanding Implications of End-of-life Preferences to Optimize Advance Care Planning Among Older AmericansR01AG059733 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BURKE, JAMES FRANCIS, SKOLARUS, LESLI ELIZABETH · 2018 to 2022
$3.1M
A Community Based Participatory Trial to Increase Stroke TreatmentU01MD010579 · NIMHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROWN, DEVIN L · 2016 to 2020
$2.8M
Identifying lifelong factors that impact brain health and outcomes in type 1 diabetes: The Cognition and Longitudinal Assessments of Risk Factors over 30 Years (CLARiFY) Diabetes Complications StudyR01DK129320 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FELDMAN, EVA LUCILLE · 2021 to 2025
$2.3M
UM Clinical Neuroscientist Training ProgramR25NS089450 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALBIN, ROGER L · 2014 to 2023
$1.3M
NCATS NIH HHS UL1 TR002240NCATS NIH HHS UL1TR002240NIA NIH HHS R01 AG059733NIA NIH HHS R01AG059733NIA NIH HHS R21 AG071796NIA NIH HHS R21AG071796NIDDK NIH HHS K24 DK002926NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30-DK-02926NIDDK NIH HHS P30 DK089503NIDDK NIH HHS P30-DK089503NIDDK NIH HHS P30 DK092926NIDDK NIH HHS R01 DK115687NIDDK NIH HHS R01DK115687NIDDK NIH HHS R01 DK129320NIDDK NIH HHS R01 DK130913NIDDK NIH HHS R24 DK082841NIDDK NIH HHS R43 DK126592NIMHD NIH HHS R01 MD011516NIMHD NIH HHS R01MD011516NIMHD NIH HHS U01 MD010579NIMHD NIH HHS U01MD010579NINDS NIH HHS R01DK130913NINDS NIH HHS R25 NS089450
6 · The paper itself

Abstract

Diabetic retinopathy, neuropathy, and nephropathy occur in more than 50% of people with diabetes, contributing substantially to morbidity and mortality. Patient understanding of these microvascular complications is essential to ensure early recognition and treatment of these sequalae as well as associated symptoms, yet little is known about patient knowledge of microvascular sequalae. In this comprehensive literature review, we provide an overview of existing knowledge regarding patient knowledge of diabetes, retinopathy, neuropathy, and nephropathy. We also discuss health care provider's knowledge of these sequalae given that patients and providers must work together to achieve optimal care. We evaluated 281 articles on patient and provider knowledge of diabetic retinopathy, neuropathy, and nephropathy as well as predictors of improved knowledge and screening practices. Results demonstrated that patient and provider knowledge of microvascular sequalae varied widely between studies, which may reflect sociocultural or methodologic differences. Knowledge assessment instruments varied between studies with limited validation data and few studies controlled for confounding. Generally, improved patient knowledge was associated with greater formal education, longer diabetes duration, and higher socioeconomic status. Fewer studies examined provider knowledge of sequalae, yet these studies identified multiple misconceptions regarding appropriate screening practices for microvascular complications and the need to screen patients who are asymptomatic. Further investigations are needed that use well validated measures, control for confounding, and include diverse populations. Such studies will allow identification of patients and providers who would benefit from interventions to improve knowledge of microvascular complications and, ultimately, improve patient outcomes.

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesDiabetic RetinopathyRetinal DiseasesHealth PersonnelHumansNephropathyNeuropathyNursePharmacistRetinopathyUnderstanding

Identifiers

PMID36322296
PMCPMC10202021

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.