SynthesisEuropean journal of nutrition2023
Dietary trans fatty acids and risk of colorectal cancer: a systematic review and meta-analysis of observational studies.
Synthesis in European journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Article
- The advent of precision nutrigeroscience in cancer: from clinic towards molecular biology.Journal of advanced research · 2026Review
- [Dietary secoisolariciresinol diglucoside alleviates chronic kidney disease in offspring rats caused by maternal trans-fatty acid exposure by regulating the Bcl-2/Bax/caspase-3 signaling axis].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- Dietary patterns and colorectal cancer: a multicenter case-control study in an Iranian population.Scientific reports · 2025Article
- Burden of gastrointestinal cancers in Asia, 1990-2019.BMC gastroenterology · 2025Article
- The association between the vitamin B1 intake and risk of non-melanoma skin cancer in U.S. adults: a cross-sectional study.Frontiers in nutrition · 2025Article
- Current Insights into Industrial Trans Fatty Acids Legal Frameworks and Health Challenges in the European Union and Spain.Foods (Basel, Switzerland) · 2024Article
- Associations between diet and nutritional supplements and colorectal cancer: A systematic review.JGH open : an open access journal of gastroenterology and hepatology · 2024Article
- Association of soy intake and cooking methods with colorectal polyp and adenoma prevalence: findings from the extended Lanxi pre-colorectal cancer cohort (LP3C).Frontiers in nutrition · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAlthough trans fatty acid has been associated with diabetes and cardiovascular disorders, studies gave conflicting results when examined their impact on colorectal cancer (CRC). The present systematic review and meta-analysis aimed to summarize the current evidence regarding the association between dietary and tissue trans fatty acids and the risk of CRC.
methodsWe searched PubMed/MEDLINE, EMBASE, Scopus, Web of Science (ISI), and Google Scholar without date and language limitation up to May 2022 and included the eligible studies. The quality of included studies was assessed using the Newcastle-Ottawa scale. The overall odds ratios (ORs) were derived using a random-effects model.
resultsIn assessment of dietary trans fatty acids 18 studies, including eight cohort, 10 case-control, and observational data from one randomized control trial were included. Although Dietary trans fats were associated with higher risk of CRC (OR = 1.093, 95% CI 1.017, 1.176, P = 0.016; I
conclusionDietary trans fatty acids increased the risk of CRC, whereas tissue trans fatty acids had a protective effect on CRC. Nonetheless, neither type of trans fatty acid increased the risk of colon or rectal cancer; thus, more prospective studies are needed to determine the validity of these associations.
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