Evidence map›Paper›PMID 36322269›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2023

Investigating gender-based differential item functioning on the Kansas City Cardiomyopathy Questionnaire (KCCQ) using qualitative content analysis.

Theresa M Coles, Nicole Lucas, Molly McFatrich, Debra Henke, Jennifer L Ridgeway, Emma M Behnken, Kevin Weinfurt, Bryce B Reeve, Amy Corneli, Shannon M Dunlay and 8 more

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

18 authors.

Theresa M ColesDepartment of Population Health Sciences, Center for Health Measurement, Duke University, Durham, NC, USA. Theresa.Coles@Duke.edu.ORCID http://orcid.org/0000-0003-2941-8999
Nicole LucasDepartment of Population Health Sciences, Center for Health Measurement, Duke University, Durham, NC, USA.
Molly McFatrichDepartment of Population Health Sciences, Center for Health Measurement, Duke University, Durham, NC, USA.
Debra HenkeDepartment of Population Health Sciences, Center for Health Measurement, Duke University, Durham, NC, USA.
Jennifer L RidgewayMayo Clinic, Rochester, NY, USA.
Emma M BehnkenMayo Clinic, Rochester, NY, USA.
Kevin WeinfurtDepartment of Population Health Sciences, Center for Health Measurement, Duke University, Durham, NC, USA.
Bryce B ReeveDepartment of Population Health Sciences, Center for Health Measurement, Duke University, Durham, NC, USA.
Amy CorneliDepartment of Population Health Sciences, Center for Health Measurement, Duke University, Durham, NC, USA.
Shannon M DunlayMayo Clinic, Rochester, NY, USA.
John A SpertusSaint Luke's Mid America Heart Institute, University of Missouri Kansas City, Kansas City, MO, USA.
Li LinDepartment of Population Health Sciences, Center for Health Measurement, Duke University, Durham, NC, USA.
Ileana L PiñaWayne State University, Detroit, Michigan, USA.
Fraser D BocellCenter for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Michelle E TarverCenter for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Heidi DohseTour de Heart, Hailey, ID, USA.
Anindita SahaCenter for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Brittany CaldwellCenter for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.

Funding

Advanced Heart Failure: Epidemiology and OutcomesR01HL144529 · NHLBI · MAYO CLINIC ROCHESTER · PI DUNLAY, SHANNON MARIE · 2019 to 2023
$3.6M
NHLBI NIH HHS R01 HL144529
6 · The paper itself

Abstract

purposeThe purpose of this study is to evaluate potential gender-based differences in interpreting the Kansas City Cardiomyopathy Questionnaire (KCCQ-23) and to explore if there are aspects of health-related quality of life (HRQOL) not captured by the KCCQ-23 that are important to assess in men and/or women with heart failure (HF).

methodsPatients ≥ 22 years of age with clinician-diagnosed HF and left ventricular ejection fraction ≤ 40% were recruited from two academic medical centers to participate in semi-structured concept elicitation and cognitive debriefing interviews. Enrollment was stratified by patient-identified gender (half women/half men). All interviews were conducted over the phone/web and audio recorded. Interviews were transcribed and descriptive qualitative content analysis was used to summarize findings overall and by gender.

resultsTwenty-five adults (56% women) diagnosed with HF participated. The average age was 67 years (range: 25-88). Women attributed a wider variety of symptoms to HF than men. Some participants had difficulty differentiating whether their experiences were due to HF, side effects of their medications, or age. We found very little evidence that participants interpreted KCCQ-23 items differently based on gender.

conclusionsOverall, our findings indicate that interpretation of the KCCQ-23 items were similar in men and women. However, some modifications to items may improve clarity of interpretation for a wide range of patients.

Indexed as

CardiomyopathiesHeart FailureAdultAgedFemaleHealth StatusHumansKansasMaleQuality of LifeStroke VolumeSurveys and QuestionnairesVentricular Function, LeftDifferential item functioningHeart failurePatient-reported outcomesQualitativeWomen

Identifiers

PMID36322269
PMCPMC9628332

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.