Evidence map›Paper›PMID 36322226›Full record

ReviewSleep & breathing = Schlaf & Atmung2023

Emerging role of metabolomics for biomarker discovery in obstructive sleep apnea.

Mohit, Manendra Singh Tomar, Deepak Sharma, Shiv Nandan, Ankit Pateriya, Ashutosh Shrivastava, Pooran Chand

Abstract readReview
PubMed Publisher
In one paragraph

Review in Sleep & breathing = Schlaf & Atmung, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Metabolomic profiles predict clinical severity in patients with obstructive sleep apnea-hypopnea syndrome.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

MohitDepartment of Prosthodontics, King George's Medical University Lucknow, Uttar Pradesh, Lucknow, 226003, India.
Manendra Singh TomarCenter for Advance Research, King George's Medical University Lucknow, Uttar Pradesh, Lucknow, 226003, India.
Deepak SharmaCouncil of Scientific & Industrial Research, Phytochemistry Division, National Botanical Research Institute, Uttar Pradesh, Lucknow, 226001, India.
Shiv NandanDepartment of Biotechnology, Era's Lucknow Medical College & Hospital, Uttar Pradesh, Lucknow, 226003, India.
Ankit PateriyaCenter for Advance Research, King George's Medical University Lucknow, Uttar Pradesh, Lucknow, 226003, India.
Ashutosh ShrivastavaCenter for Advance Research, King George's Medical University Lucknow, Uttar Pradesh, Lucknow, 226003, India. ashutoshshrivastava@kgmcindia.edu.
Pooran ChandDepartment of Prosthodontics, King George's Medical University Lucknow, Uttar Pradesh, Lucknow, 226003, India. dr.pooran_chand@yahoo.com.
King George's Medical University · INCouncil of Scientific and Industrial Research · INEra's Lucknow Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) is characterized by the complete or partial blockage of the upper airway passage during sleep which causes repetitive breaks in sleep and may result in excessive daytime sleepiness. OSA has been linked to various metabolic disorders and chronic health conditions, such as obesity, diabetes, hypertension, and depression. Profiling of alterations in metabolites and their regulation in OSA has been hypothesized to be an effective approach for early diagnosis and prognosis of OSA. Several studies have characterized metabolic fingerprints associated with sleep disorders. There is a lack of understanding of metabolite contents and their alterations in OSA that may help to identify specific biomarkers. The information provided in this review will help update new methodologies and interventions of high throughput advanced molecular/metabolomics tools which may clarify the metabolic aspects and mechanisms for improved management and treatment of OSA.

Indexed as

HypertensionSleep Apnea, ObstructiveBiomarkersHumansMetabolomicsPrognosisBiomarkersBiomarker discoveryGas chromatographyLiquid chromatographyMass spectrometryMetabolomicsObstructive sleep apnea

Identifiers

PMID36322226
OpenAlexW4307936076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.