Evidence map›Paper›PMID 36321810›Full record

ArticleeLife2022

Altered basal ganglia output during self-restraint.

Bon-Mi Gu, Joshua D Berke

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bon-Mi GuDepartment of Neurology, University of California, San Francisco, San Francisco, United States.ORCID 0000-0002-3060-0803
Joshua D BerkeDepartment of Neurology, University of California, San Francisco, San Francisco, United States.ORCID 0000-0003-1436-6823
University of California, San Francisco · US

Funding

Striatal Microcircuit DynamicsR01NS123516 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BERKE, JOSHUA D · 2021 to 2025
$2.1M
Basal Ganglia Pathways for Stopping and SwitchingR01MH101697 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BERKE, JOSHUA D · 2013 to 2017
$1.9M
NIMH NIH HHS R01 MH101697NINDS NIH HHS R01 NS123516
6 · The paper itself

Abstract

Suppressing actions is essential for flexible behavior. Multiple neural circuits involved in behavioral inhibition converge upon a key basal ganglia output nucleus, the substantia nigra pars reticulata (SNr). To examine how changes in basal ganglia output contribute to self-restraint, we recorded SNr neurons during a proactive behavioral inhibition task. Rats responded to

Indexed as

Pars ReticulataSubstantia NigraAnimalsBasal GangliaNeuronsRatsReaction Timebehavioral inhibitionneuroscienceparkinson's diseasepopulation dynamicsratspike variabilitysubstantia nigra pars reticulata

Identifiers

PMID36321810
PMCPMC9665843
OpenAlexW4307972683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.