Evidence map›Paper›PMID 36321671›Full record

ArticleJournal of cardiac surgery2022

On- versus off-pump CABG in octogenarians: A propensity-matched analysis from the UK National Database.

Jeremy Chan, Arnaldo Dimagli, Daniel P Fudulu, Tim Dong, Ester Mikova, Gianni D Angelini

Open access · hybridAbstract read
In one paragraph

Article in Journal of cardiac surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jeremy ChanBristol Heart Institute, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-3009-5712
Arnaldo DimagliBristol Heart Institute, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0003-0055-8656
Daniel P FuduluBristol Heart Institute, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0001-6759-7719
Tim DongBristol Heart Institute, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0003-1953-0063
Ester MikovaBristol Heart Institute, University of Bristol, Bristol, UK.
Gianni D AngeliniBristol Heart Institute, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-1753-3730
University of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCoronary artery bypass grafting (CABG) remains a good revascularization strategy in octogenarians with excellent clinical outcomes and quality of life postoperatively. However, the benefits of off-pump over on-pump CABG in the elderly population are still controversial. We investigated this issue in the UK National Audit database.

methodWe retrospectively analyzed all octogenarians undergoing nonemergency, isolated CABG from 1996 to 2019. Propensity score matching (PSM) was conducted to adjust for imbalance in the baseline characteristics between the off-pump and on-pump groups. Primary outcome was in-hospital mortality and postoperative cerebrovascular accidents. Secondary outcomes were bleeding requiring reoperation, deep sternal wound infection, and postoperative dialysis.

resultA total of 6436 patients were included for analysis. No differences were observed between off- and on-pump group in-hospital mortality (4% vs. 3.8%, p = .89), return to theater rate (5.4% vs. 6.2%, p = .16) and incidence of deep sternal wound infection (1.1% vs. 1.6%, p = .34). However, octogenarian undergoing off-pump CABG were less likely to experience postoperative transient ischemic attack (TIA)/stroke (1.4% vs. 2.3%, p = .004) but more likely to require renal dialysis (4.8% vs. 3.5%, p = .03).

conclusionThe data show similar in-hospital mortality in octogenarians regardless of the revascularization technique used. Off-pump when compared with on-pump CABG is associated with a lower incidence in postoperative neurological events but a higher need for renal dialysis.

Indexed as

Coronary Artery DiseaseOctogenariansAgedAged, 80 and overCoronary Artery BypassHumansPostoperative ComplicationsQuality of LifeRenal DialysisRetrospective StudiesTreatment OutcomeUnited KingdomCoronary artery bypass graftingOctogenariansOff Pump

Identifiers

PMID36321671
PMCPMC10092246
OpenAlexW4307920671

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.