Evidence map›Paper›PMID 36321496›Full record

ArticleProceedings. Biological sciences2022

Severe inbreeding, increased mutation load and gene loss-of-function in the critically endangered Devils Hole pupfish.

David Tian, Austin H Patton, Bruce J Turner, Christopher H Martin

Open access · hybridAbstract read
In one paragraph

Article in Proceedings. Biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  8. Rapid vertebrate speciation via isolation, bottlenecks, and drift.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

David TianDepartment of Integrative Biology, University of California, Berkeley, CA 94720, USA.ORCID 0000-0001-5285-6810
Austin H PattonDepartment of Integrative Biology, University of California, Berkeley, CA 94720, USA.ORCID 0000-0003-1286-9005
Bruce J TurnerMuseum of Vertebrate Zoology, University of California, Berkeley, CA 94720, USA.
Christopher H MartinDepartment of Integrative Biology, University of California, Berkeley, CA 94720, USA.ORCID 0000-0001-7989-9124
Museum of Vertebrate Zoology · US

Funding

Discovery and functional analysis of novel candidate genes and variants underlying craniofacial diversification in Cyprinodon pupfishesR01DE027052 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Christopher Herbert Martin · 2018 to 2026
$3.0M
NIDCR NIH HHS R01 DE027052
6 · The paper itself

Abstract

Small populations with limited range are often threatened by inbreeding and reduced genetic diversity, which can reduce fitness and exacerbate population decline. One of the most extreme natural examples is the Devils Hole pupfish (

Indexed as

InbreedingKillifishesAnimalsEndangered SpeciesGenetic VariationHumansMaleMutationSperm MotilityDevils Hole pupfishinbreedingmutation loadruns of homozygosity

Identifiers

PMID36321496
PMCPMC9627712
OpenAlexW4307869023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.