ArticleAfrican health sciences2022
Longitudinal patients' cohorts for impactful research and HIV care at the Infectious Diseases Institute.
Article in African health sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- A programmatic assessment of dolutegravir adverse events and discontinuations in Uganda.HIV medicine · 2025Article
- Socio-behavioral determinants of early vs. long-term HIV infection in Kazakhstan: roles of self-testing, alcohol, drug use and sexual networks.Frontiers in public health · 2025Article
- Barriers and facilitators of adherence to long-term antiretroviral treatment in Kampala, Uganda.PLOS global public health · 2025Article
- Article
- Experiences and lessons learned from a global research administration capacity building project to support and expand HIV/AIDS research in southwestern Uganda.Discover health systems · 2024Article
- A century of Makerere and 22 years of academic publishing: African Health Sciences into a new gear.African health sciences · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Observational studies provide important evidence supporting the feasibility and effectiveness of health interventions. The 20-year-old Infectious Diseases Institute (IDI) established to respond to infectious diseases, specifically HIV/AIDS, invested in the set-up of longitudinal cohorts. In this paper we discuss the results of these cohorts and their impact on the response to the HIV pandemic in Uganda. Methods: IDI invested in experienced system developers, clinic and laboratory capacity to create the infrastructure to host longitudinal cohorts. Several cohorts were created, including patients initiated and followed up on ART, specialized cohorts (e.g. TB co-infection) and long-term cohorts with patients on ART for over 10 years and aged 60 and above. These cohorts function as platforms for sub-studies, attracting collaborators and students. Results: Data from the IDI cohorts contributed evidence to ART programs on when to start, which drugs to use, how to best monitor and which models of care to implement. Sub-studies contributed to management of opportunistic infections, understanding immunological response and the emerging complications of non-communicable diseases. Conclusion: Cohorts provide a platform for clinical care, training, and research to inform strategic responses and put Makerere University at the center of the response to the HIV pandemic in the region.
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Registered trials
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