Evidence map›Paper›PMID 36320879›Full record

ArticleCurrent health sciences journal

Biocompatibility Studies on a Collagen-Hydroxyapatite Biomaterial.

Oana-Liliana Filip Ionescu, Andreea Gabriela Mocanu, Ionela Andreea Neacşu, Maria-Viorica Ciocîlteu, Gabriela Rău, Johny Neamţu

Abstract read
In one paragraph

Article in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Revolutionizing bone healing: the role of 3D models.Cell regeneration (London, England) · 2025
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Oana-Liliana Filip IonescuFaculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Romania.
Andreea Gabriela MocanuFaculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Romania.
Ionela Andreea NeacşuFaculty of Appplied Chemistry and Materials Science, Politehnica University of Bucharest, Romania.
Maria-Viorica CiocîlteuFaculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Romania.
Gabriela RăuFaculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Romania.
Johny NeamţuFaculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current treatment of osteomyelitis includes systemic antibiotic therapy and a debridement procedure of the formed biofilm and necrotic tissue. Moreover, cements and three-dimensional scaffolds are used both for the delivery of therapeutic agents and as fillers for bone defects. The aim of our research was to test, on cellular cultures, the biocompatibility of a previously synthesized microporous biocomposite containing hydroxyapatite and a collagen matrix including a therapeutic agent (ciprofloxacin and gentamicin). The scaffold was obtained by direct mineralization namely co-precipitation of hydroxyapatite on a collagen matrix.

Indexed as

biocompatibilityBiocompositecollagen-hydroxyapatite

Identifiers

PMID36320879
PMCPMC9590366

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.