Evidence map›Paper›PMID 36320871›Full record

ArticleCurrent health sciences journal

Prediction of Preterm Birth with Serial Measurements of Ultrasound Markers.

Ioana Victoria Camen, Maria Magdalena Manolea, Sidonia Catalina Vrabie, Maria Sidonia Sandulescu, Mircea Sebastian Serbanescu, Mihail Virgil Boldeanu, Liliana Novac, Anca Maria Istrate-Ofiteru, Simona Daniela Neamtu, Anda Lorena Dijmarescu

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Article in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Ioana Victoria CamenPh.D. student, Doctoral School, University of Medicine and Pharmacology of Craiova, Romania.
Maria Magdalena ManoleaObstetrics and Gynecology Department, University of Medicine and Pharmacology of Craiova, Romania.
Sidonia Catalina VrabieObstetrics and Gynecology Department, University of Medicine and Pharmacology of Craiova, Romania.
Maria Sidonia SandulescuObstetrics and Gynecology Department, University of Medicine and Pharmacology of Craiova, Romania.
Mircea Sebastian SerbanescuMedical Informatics Department, University of Medicine and Pharmacology of Craiova, Romania.
Mihail Virgil BoldeanuImmunology Department, University of Medicine and Pharmacy of Craiova, Romania.
Liliana NovacObstetrics and Gynecology Department, University of Medicine and Pharmacology of Craiova, Romania.
Anca Maria Istrate-OfiteruDepartment of Histology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania.
Simona Daniela NeamtuDepartment of Hematology, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Romania.
Anda Lorena DijmarescuObstetrics and Gynecology Department, University of Medicine and Pharmacology of Craiova, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To compare the ability of cervical length (CL), anterior cervical angle (ACA), and cervical consistency index (CCI) to predict premature birth.

methodsThis prospective study involved 85 pregnant women who gave birth prematurely and a control group of 31 pregnant women who gave birth at term. The study was performed in the Obstetrics and Gynecology Clinic of the Municipal Clinical Hospital Filanthropia Craiova between January 1, 2019, and January 1, 2022. Cases were examined using transvaginal ultrasonography (TVU) in the second and third trimesters of pregnancy, and cervical length (CL), Anterior Cervical Angle (ACA), and Cervical Consistency Index (CCI) were measured.

resultsThe mean value from the three measurements at all three parameters was statistically significant with preterm birth (p<0.05). Cervical length <25mm, was highly significant in the prediction of preterm labor with a sensitivity of 99%, specificity of 61%, positive predictive value (PPV) of 78%, negative predictive value (NPV) of 97 %, and a positive likelihood ratio (LR+) of 2.54 and negative likelihood ratio (LR-) of 0.02. CCI also remains, despite low specificity and PPV values, a potential predictive parameter in the prediction of preterm birth, with a sensitivity of 73%, NPV of 92% and a LR+of 1.32 and LR- of 0.6 also correlated with CL, CCI being more difficult to interpret as an independent predictive parameter.

conclusionsCL remains the standard parameter for predicting the preterm birth, but in combination with other parameters, the prediction rate can increase significantly.

Indexed as

anterior cervical anglecervical consistency indexcervical lengthpreterm birth

Identifiers

PMID36320871
PMCPMC9590368

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