Evidence map›Paper›PMID 36320870›Full record

ArticleCurrent health sciences journal

VEGF Immunoexpression in Endometrioid Endometrial Carcinomas.

Ileana Drocaş, Ştefania Crăiţoiu, Alex Emilian Stepan, Cristiana Eugenia Simionescu, Daniela Marinescu

Abstract read
In one paragraph

Article in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ileana DrocaşPhD Student, Department of Histology, University of Medicine and Pharmacy of Craiova, Romania.
Ştefania CrăiţoiuDepartment of Histology, University of Medicine and Pharmacy of Craiova, Romania.
Alex Emilian StepanDepartment of Pathology, University of Medicine and Pharmacy of Craiova, Romania.
Cristiana Eugenia SimionescuDepartment of Pathology, University of Medicine and Pharmacy of Craiova, Romania.
Daniela MarinescuDepartment of General Surgery, University of Medicine and Pharmacy of Craiova.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular endothelial growth factor (VEGF) is the most important stimulator of endometrial tumor angiogenesis, a mechanism that may be a therapeutic target in the context of an incidence and persistent mortality of endometrial endometrial carcinomas (EEC). In this study, VEGF immunoexpression was analyzed for 50 cases of EEC in relation to the histopathological parameters of tumor aggressiveness. High VEGF scores have been associated with the high grade and advanced stage of EEC, but unrelated to the depth of myometrial invasion, the pattern of tumor invasion, or vascular invasion. VEGF may be useful for assessing EEC aggression, but also for tumor angiogenic potential, which recommends it as a possible mark for specific antitumor therapy.

Indexed as

Endometrioid endometrial carcinomastumor gradetumor stageVEGF

Identifiers

PMID36320870
PMCPMC9590369

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.