Evidence map›Paper›PMID 36320832›Full record

ArticleRSC advances2022

Titanate nanoribbon-based nanobiohybrid for potential applications in regenerative medicine.

Lionel Maurizi, Vanessa Bellat, Mathieu Moreau, Emmanuel De Maistre, Julien Boudon, Laure Dumont, Franck Denat, David Vandroux, Nadine Millot

Abstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lionel MauriziLaboratoire Interdisciplinaire Carnot de Bourgogne, UMR 6303 CNRS/Université Bourgogne Franche-Comté 9 Avenue Alain Savary BP 47870 21078 Dijon France nadine.millot@u-bourgogne.fr.ORCID https://orcid.org/0000-0002-6346-7623
Vanessa BellatLaboratoire Interdisciplinaire Carnot de Bourgogne, UMR 6303 CNRS/Université Bourgogne Franche-Comté 9 Avenue Alain Savary BP 47870 21078 Dijon France nadine.millot@u-bourgogne.fr.
Mathieu MoreauInstitut de Chimie Moléculaire de l'Université de Bourgogne, UMR 6302 CNRS/Université Bourgogne Franche-Comté 9 Avenue Alain Savary BP 47870 21078 Dijon France.
Emmanuel De MaistreHaemostasis Unit, University Hospital of Dijon Dijon France.
Julien BoudonLaboratoire Interdisciplinaire Carnot de Bourgogne, UMR 6303 CNRS/Université Bourgogne Franche-Comté 9 Avenue Alain Savary BP 47870 21078 Dijon France nadine.millot@u-bourgogne.fr.ORCID https://orcid.org/0000-0002-2500-5030
Laure DumontSociété NVH Medicinal Dijon France david.vandroux@nvh-medicinal.com.
Franck DenatInstitut de Chimie Moléculaire de l'Université de Bourgogne, UMR 6302 CNRS/Université Bourgogne Franche-Comté 9 Avenue Alain Savary BP 47870 21078 Dijon France.ORCID https://orcid.org/0000-0002-9652-4006
David VandrouxSociété NVH Medicinal Dijon France david.vandroux@nvh-medicinal.com.
Nadine MillotLaboratoire Interdisciplinaire Carnot de Bourgogne, UMR 6303 CNRS/Université Bourgogne Franche-Comté 9 Avenue Alain Savary BP 47870 21078 Dijon France nadine.millot@u-bourgogne.fr.ORCID https://orcid.org/0000-0002-0127-3858

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticles capable of mimicking natural tissues represent a major technological advancement in regenerative medicine. In this pilot study, the development of a new nanohybrid composed of titanate nanoribbons to mimic the extracellular matrix is reported. During the first phase, nanoribbons were synthesized by hydrothermal treatment. Subsequently, titanate nanoribbons were functionalized by heterobifunctional polyethylene-glycol (PEG) to graft type I collagen on their surface. Biological properties of this new nanobiohybrid such as cytotoxicity to cardiac cells and platelet aggregation ability were evaluated. The so-formed nanobiohybrid permits cellular adhesion and proliferation favoring fine cardiac tissue healing and regeneration.

Identifiers

PMID36320832
PMCPMC9490774

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.