Evidence map›Paper›PMID 36320782›Full record

ArticleRSC advances2022

Graphene oxide reinforced silk fibroin nanocomposite as an electroactive interface for the estimation of dopamine.

Afifa Noor, Hamad Khalid, Muhammad Aslam, Akhtar Hayat, Ather Farooq Khan, Muhammad Nasir, Aqif Anwar Chaudhry, Mian Hasnain Nawaz

Abstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Afifa NoorInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad Lahore Campus 54000 Pakistan hamadkhalid@cuilahore.edu.pk mhnawaz@cuilahore.edu.pk.
Hamad KhalidInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad Lahore Campus 54000 Pakistan hamadkhalid@cuilahore.edu.pk mhnawaz@cuilahore.edu.pk.
Muhammad AslamDepartment of Chemistry, Division of Science and Technology, University of Education Lahore 54000 Pakistan.
Akhtar HayatInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad Lahore Campus 54000 Pakistan hamadkhalid@cuilahore.edu.pk mhnawaz@cuilahore.edu.pk.
Ather Farooq KhanInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad Lahore Campus 54000 Pakistan hamadkhalid@cuilahore.edu.pk mhnawaz@cuilahore.edu.pk.
Muhammad NasirInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad Lahore Campus 54000 Pakistan hamadkhalid@cuilahore.edu.pk mhnawaz@cuilahore.edu.pk.
Aqif Anwar ChaudhryInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad Lahore Campus 54000 Pakistan hamadkhalid@cuilahore.edu.pk mhnawaz@cuilahore.edu.pk.
Mian Hasnain NawazInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad Lahore Campus 54000 Pakistan hamadkhalid@cuilahore.edu.pk mhnawaz@cuilahore.edu.pk.ORCID https://orcid.org/0000-0002-6648-0778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fabrication of 2D materials and polymer-based nanocomposites deposited on flexible conductive interfaces has unblocked new horizons to expedite reaction kinetics for developing highly selective and sensitive electrochemical biosensors. Herein, we developed a novel biosensing platform, comprising graphene oxide and a silk fibroin-based nanocomposite, drop-cast on a carbon cloth electrode. The fabricated interface was expected to be a robust and miniaturized sensing platform for precise detection of dopamine (DA). Characterization was performed by SEM, EDX, FTIR, XRD, UV-visible spectroscopy, contact angle measurement, fluorescence spectroscopy, particle size, and zeta potential analysis. CV, EIS, DPV, and chronoamperometry demonstrated the superior electrochemical properties of the working interface and revealed its enhanced active surface area, increased conductivity, and accelerated electron transfer rate. The designed interface exhibited low LoD (0.41 μM), admirable stability, good sensitivity (2.46 μA μM

Identifiers

PMID36320782
PMCPMC9557168

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.