ReviewRSC advances2022
1,4-Dihydropyridine: synthetic advances, medicinal and insecticidal properties.
Review in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Design, Synthesis, and Self-Assembly of Amphiphilic 1,4-Dihydropyridines Containing Branched Ester Moieties.Molecules (Basel, Switzerland) · 2026Article
- Iron-catalyzed divergent synthesis of coumarin fused N-heterocyclesRSC advances · 2025Article
- A Decade of Catalytic Progress in 1,4-Dihydropyridines (1,4-DHPs) Synthesis (2016-2024).Current organic synthesis · 2025Article
- Designing 1,4-Dihydropyridines-Based Multitarget Therapeutics: Recent Advances and Future Directions.Current topics in medicinal chemistry · 2025Review
- The significance of chirality in contemporary drug discovery-a mini review.RSC advances · 2024Review
- Montmorillonite K-10 catalyzed synthesis of Hantzsch dihydropyridine derivatives from methyl arenesRSC advances · 2024Article
- Acyl-1,4-Dihydropyridines: Universal Acylation Reagents for Organic Synthesis.Molecules (Basel, Switzerland) · 2024Review
- Facile One-Pot Synthesis and Anti-Microbial Activity of Novel 1,4-Dihydropyridine Derivatives in Aqueous Micellar Solution under Microwave Irradiation.Molecules (Basel, Switzerland) · 2024Article
- Development of Self-AssemblingMolecules (Basel, Switzerland) · 2023Article
- Iodine catalyzed synthesis of imidazo[1,2-RSC advances · 2023Article
- Mechanisms of dihydropyridine agonists and antagonists in view of cryo-EM structures of calcium and sodium channels.The Journal of general physiology · 2023Article
- Article
- Metallated dihydropyridinates: prospects in hydride transfer and (electro)catalysis.Chemical science · 2023Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
1,4-Dihydropyridine (1,4-DHP) is one of the foremost notable organic scaffolds with diverse pharmaceutical applications. This study will highlight recent accomplishments in the construction of 1,4-DHP with structural and functional modifications using multi-component one-pot and green synthetic methodologies. The various intrinsic therapeutic applications, ranging from calcium channel blocker, anti-oxidative, anticancer, anti-inflammatory, anti-microbial, anti-hypertensive, anti-diabetic, anticoagulants, anti-cholinesterase, neuro-protective, and other miscellaneous activities, have been summarized with a focus on their structure-activity relationship (SAR) investigations. In addition, the insecticidal properties have been collated and discussed. Researchers in the fields of medicinal chemistry and drug development will find the summarized conclusions of this study incredibly informative, instructional, and valuable.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.