Evidence map›Paper›PMID 36320663›Full record

ArticleBiosafety and health2022

An imported human case with the SARS-CoV-2 Omicron subvariant BA.2.75 in Yunnan Province, China.

Meiling Zhang, Zhixiao Chen, Jienan Zhou, Xiaonan Zhao, Yaoyao Chen, Yanhong Sun, Zhaosheng Liu, Wenpeng Gu, Chunrui Luo, Xiaoqing Fu and 1 more

Abstract read
In one paragraph

Article in Biosafety and health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Meiling ZhangYunnan Center for Disease Control and Prevention, Kunming 650022, China.
Zhixiao ChenNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Jienan ZhouYunnan Center for Disease Control and Prevention, Kunming 650022, China.
Xiaonan ZhaoYunnan Center for Disease Control and Prevention, Kunming 650022, China.
Yaoyao ChenYunnan Center for Disease Control and Prevention, Kunming 650022, China.
Yanhong SunYunnan Center for Disease Control and Prevention, Kunming 650022, China.
Zhaosheng LiuYunnan Center for Disease Control and Prevention, Kunming 650022, China.
Wenpeng GuYunnan Center for Disease Control and Prevention, Kunming 650022, China.
Chunrui LuoYunnan Center for Disease Control and Prevention, Kunming 650022, China.
Xiaoqing FuYunnan Center for Disease Control and Prevention, Kunming 650022, China.
Xiang ZhaoNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Omicron variants spread rapidly worldwide after being initially detected in South Africa in November 2021. It showed increased transmissibility and immune evasion with far more amino acid mutations in the spike (S) protein than the previously circulating variants of concern (VOCs). Notably, on 15 July 2022, we monitored the first VOC / Omicron subvariant BA.2.75 in China from an imported case. Moreover, nowadays, this subvariant still is predominant in India. It has nine additional mutations in the S protein compared to BA.2, three of which (W152R, G446S, and R493Q reversion) might contribute to higher transmissibility and immune escape. This subvariant could cause wider spread and pose a threat to the global situation. Our timely reporting and continuous genomic analysis are essential to fully elucidate the characteristics of the subvariant BA.2.75 in the future.

Indexed as

Genomic analysisMutationsOmicron subvariantSARS-CoV-2

Identifiers

PMID36320663
PMCPMC9613801

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.