ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2022
Speech and language characteristics differentiate Alzheimer's disease and dementia with Lewy bodies.
Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Digital Biomarkers for the Assessment of Non-Cognitive Symptoms in Patients with Dementia with Lewy Bodies: A Systematic Review.Journal of Alzheimer's disease : JAD · 2024Pooled it
- Assessment of Language Impairments Towards Identifying Markers for Early Diagnosis of Pathological Cognitive Decline.Behavioral sciences (Basel, Switzerland) · 2026Review
- Vocal Feature Changes for Monitoring Parkinson's Disease Progression-A Systematic Review.Brain sciences · 2025Review
- Clinical Decision Support Using Speech Signal Analysis: Systematic Scoping Review of Neurological Disorders.Journal of medical Internet research · 2025Article
- High frequency post-pause word choices and task-dependent speech behavior characterize connected speech in individuals with mild cognitive impairment.medRxiv : the preprint server for health sciences · 2024Article
- Speech patterns during memory recall relates to early tau burden across adulthood.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Shifting From Active to Passive Monitoring of Alzheimer Disease: The State of the Research.Journal of the American Heart Association · 2024Review
- Distinct eye movement patterns to complex scenes in Alzheimer's disease and Lewy body disease.Frontiers in neuroscience · 2024Article
- New Insights into Potential Biomarkers in Patients with Mild Cognitive Impairment Occurring in the Prodromal Stage of Dementia with Lewy Bodies.Brain sciences · 2023Review
- Speech and language characteristics differentiate Alzheimer's disease and dementia with Lewy bodies.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- Vocal expression of emotions discriminates dementia with Lewy bodies from Alzheimer's disease.Alzheimer's & dementia (Amsterdam, Netherlands)Article
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Authors and funding
6 authors.
Funding
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Abstract
Introduction: Early differential diagnosis of Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) is important, but it remains challenging. Different profiles of speech and language impairments between AD and DLB have been suggested, but direct comparisons have not been investigated. Methods: We collected speech responses from 121 older adults comprising AD, DLB, and cognitively normal (CN) groups and investigated their acoustic, prosodic, and linguistic features. Results: The AD group showed larger differences from the CN group than the DLB group in linguistic features, while the DLB group showed larger differences in prosodic and acoustic features. Machine-learning classifiers using these speech features achieved 87.0% accuracy for AD versus CN, 93.2% for DLB versus CN, and 87.4% for AD versus DLB. Discussion: Our findings indicate the discriminative differences in speech features in AD and DLB and the feasibility of using these features in combination as a screening tool for identifying/differentiating AD and DLB.
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