Evidence map›Paper›PMID 36320598›Full record

ArticleJournal of pharmaceutical analysis2022

Evaluation of the chemical profile from four germplasms sources of Pruni Semen using UHPLC-LTQ-Orbitrap-MS and multivariate analyses.

Zihan Zhao, Yue Liu, Yushi Zhang, Zeyu Geng, Rina Su, Lipeng Zhou, Chao Han, Zhanjun Wang, Shuangcheng Ma, Weidong Li

Abstract read
In one paragraph

Article in Journal of pharmaceutical analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zihan ZhaoSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Yue LiuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Yushi ZhangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Zeyu GengSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Rina SuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Lipeng ZhouSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Chao HanSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Zhanjun WangInstitute of Forestry and Grassland Ecology, Ningxia Academy of Agricultural and Forestry Sciences, Yinchuan, 750002, China.
Shuangcheng MaInstitute for Control of Chinese Traditional Medicine and Ethnic Medicine, National Institutes for Food and Drug Control, Beijing, 100050, China.
Weidong LiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pruni Semen, the seed of several unique Prunus plants, is a traditional purgative herbal material. To determine the authentic sources of Pruni Semen, 46 samples from four species were collected and analyzed. Ten compounds including multiflorin A (Mul A), a notable purative compound, were isolated and identified by chemical separation and nuclear magnetic resonance spectroscopy. Seventy-six communal components were identified by ultra-high performance liquid chromatography with linear ion trap-quadrupole Orbitrap mass spectrometry, and acetyl flavonoid glycosides were recognized as characteristic constituents. The flavonoids were distributed in the seed coat and cyanogenic glycosides in the kernel. Based on this, methods for identifying Pruni Semen from different sources were established using chemical fingerprinting, quantitative analysis of the eight principal compounds, hierarchical cluster analysis, principal component analysis, and orthogonal partial least squares discriminant analysis. The results showed that the samples were divided into two categories: one is the small seeds from

Indexed as

Acetyl flavonoidsAmygdalinAuthentic sourcesMultivariate analysesPruni semen

Identifiers

PMID36320598
PMCPMC9615524

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