Evidence map›Paper›PMID 36320201›Full record

ArticleOpen forum infectious diseases2022

Demographics and Outcomes of Initial Phase of COVID-19 Medicines Delivery Units Across 4 UK Centers During Peak B1.1.529 Omicron Epidemic: A Service Evaluation.

Michael Brown, Jasjot Saund, Azka Qureshi, Megan Plowright, Katie Drury, Joshua Gahir, Tom Simpson, Thomas Newman, Kate Adams, James Galloway and 7 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Michael BrownDivision of Infection, University College London Hospitals NHS Foundation Trust, London, United Kingdom.
Jasjot SaundDivision of Infection, University College London Hospitals NHS Foundation Trust, London, United Kingdom.
Azka QureshiDepartment of Infection, Guys and St Thomas's NHS Foundation Trust, London, United Kingdom.
Megan PlowrightDepartment of Infectious Diseases and Tropical Medicine, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Katie DruryInfection Research Group, Hull University Teaching Hospitals NHS Foundation Trust, Hull, United Kingdom.
Joshua GahirDivision of Infection, University College London Hospitals NHS Foundation Trust, London, United Kingdom.
Tom SimpsonDepartment of Respiratory Medicine, Lewisham Hospital, London, United Kingdom.
Thomas NewmanDepartment of Infectious Diseases and Tropical Medicine, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Kate AdamsInfection Research Group, Hull University Teaching Hospitals NHS Foundation Trust, Hull, United Kingdom.
James GallowayCentre for Rheumatic Disease, Kings College London, London, United Kingdom.
Kezia DurairajDepartment of Infection, Guys and St Thomas's NHS Foundation Trust, London, United Kingdom.
Kamla ElgizouliInfection Research Group, Hull University Teaching Hospitals NHS Foundation Trust, Hull, United Kingdom.
Tommy RamplingDivision of Infection, University College London Hospitals NHS Foundation Trust, London, United Kingdom.
Joby ColeDepartment of Infectious Diseases and Tropical Medicine, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Nicholas EasomInfection Research Group, Hull University Teaching Hospitals NHS Foundation Trust, Hull, United Kingdom.ORCID https://orcid.org/0000-0001-6413-919X
Anna L GoodmanDepartment of Infection, Guys and St Thomas's NHS Foundation Trust, London, United Kingdom.
Michael MarksDivision of Infection, University College London Hospitals NHS Foundation Trust, London, United Kingdom.ORCID https://orcid.org/0000-0002-7585-4743

Funding

Medical Research Council MC_UU_00004/04
6 · The paper itself

Abstract

Background: COVID-19 medicines delivery units (CMDU) were established in late December 2021 to deliver early antiviral therapy to patients classified as at risk with the aim of preventing hospitalization. Methods: We performed a service evaluation at 4 CMDUs in England. We assessed demographics and triage outcomes of CMDU referral, uptake of antiviral therapy, and the rate of subsequent hospitalizations within 2 weeks of CMDU referral. Results: Over a 3-week period, 4788 patients were referred and 3989 were ultimately assessed by a CMDU. Overall, 832 of the patients referred (17%) were judged eligible for treatment and 628 (13%) were ultimately prescribed an antiviral agent. The overall rate of admission within 14 days was 1%. Patients who were admitted were significantly older than those who did not require hospitalization. Of patients prescribed molnupiravir and sotrovimab, 1.8% and 3.2%, respectively, were admitted. Conclusions: There was a high volume of referrals to CMDU service during the initial surge of the Omicron wave in the United Kingdom. A minority of patients were judged to be eligible for therapy. In a highly vaccinated population, the overall hospitalization rate was low.

Indexed as

COVID-19molnupiravirsotrovimab

Identifiers

PMID36320201
PMCPMC9605703

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.