Evidence map›Paper›PMID 36320182›Full record

Observational studyPeritoneal dialysis international : journal of the International Society for Peritoneal Dialysis2023

Outcomes of PD for AKI treatment during COVID-19 in New York City: A multicenter study.

Maryanne Y Sourial, Anirudh Gone, Jaime Uribarri, Vesh Srivatana, Shuchita Sharma, Daniil Shimonov, Michael Chang, Wenzhu Mowrey, Rochelle Dalsan, Kaltrina Sedaliu and 5 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Maryanne Y SourialDivision of Nephrology, Albert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0001-9369-693X
Anirudh GoneDivision of Nephrology, Montefiore Medical Center, Bronx, NY, USA.
Jaime UribarriDivision of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Vesh SrivatanaDivision of Nephrology and Hypertension, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0003-2998-6451
Shuchita SharmaDivision of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Daniil ShimonovDivision of Nephrology and Hypertension, Weill Cornell Medicine, New York, New York, USA.
Michael ChangDivision of Nephrology, Montefiore Medical Center, Bronx, NY, USA.
Wenzhu MowreyDivision of Biostatistics, Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Rochelle DalsanDivision of Nephrology, Albert Einstein College of Medicine, Bronx, NY, USA.
Kaltrina SedaliuDivision of Nephrology, Montefiore Medical Center, Bronx, NY, USA.
Swati JainDivision of Nephrology, Montefiore Medical Center, Bronx, NY, USA.
Michael J RossDivision of Nephrology, Albert Einstein College of Medicine, Bronx, NY, USA.
Nina CaplinDivision of Nephrology, New York University Langone Health and New York University Grossman School of Medicine, New York, NY, USA.
Wei ChenDivision of Nephrology, Albert Einstein College of Medicine, Bronx, NY, USA.
New York City Peritoneal Dialysis Consortium

Funding

Novel mechanisms of antiretroviral protection against HIV-related kidney diseasesR01DK101338 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ROSS, MICHAEL J · 2014 to 2018
$1.9M
The role of APOL1 polymorphisms in promoting HIV-related kidney injuryR01DK108346 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ROSS, MICHAEL J · 2015 to 2019
$1.6M
Calcification Propensity, using Dynamic Light Scattering, to Study Vascular Calcification in Patients with Advanced Chronic Kidney DiseaseK23DK114476 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CHEN, WEI · 2018 to 2021
$953k
Cellular Interactions in Vascular Calcification of Chronic Kidney DiseaseR03DK131246 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI CHEN, WEI · 2022 to 2023
$251k
NIDDK NIH HHS K23 DK114476NIDDK NIH HHS L30 DK106721NIDDK NIH HHS L30 DK133984NIDDK NIH HHS R01 DK101338NIDDK NIH HHS R01 DK108346NIDDK NIH HHS R03 DK131246
6 · The paper itself

Abstract

backgroundThe high incidence of acute kidney injury (AKI) requiring dialysis associated with COVID-19 led to the use of peritoneal dialysis (PD) for the treatment of AKI. This study aims to compare in-hospital all-cause mortality and kidney recovery between patients with AKI who received acute PD versus extracorporeal dialysis (intermittent haemodialysis and continuous kidney replacement therapy).

methodsIn a retrospective observational study of 259 patients with AKI requiring dialysis during the COVID-19 surge during Spring 2020 in New York City, we compared 30-day all-cause mortality and kidney recovery between 93 patients who received acute PD at any time point and 166 patients who only received extracorporeal dialysis. Kaplan-Meier curves, log-rank test and Cox regression were used to compare survival and logistic regression was used to compare kidney recovery.

resultsThe mean age was 61 ± 11 years; 31% were women; 96% had confirmed COVID-19 with median follow-up of 21 days. After adjusting for demographics, comorbidities, oxygenation and laboratory values prior to starting dialysis, the use of PD was associated with a lower mortality rate compared to extracorporeal dialysis with a hazard ratio of 0.48 (95% confidence interval: 0.27-0.82,

conclusionsThe use of PD for the treatment of AKI was not associated with worse clinical outcomes when compared to extracorporeal dialysis during the height of the COVID-19 pandemic in New York City. Given the inherent selection biases and residual confounding in our observational study, research with a larger cohort of patients in a more controlled setting is needed to confirm our findings.

Indexed as

Acute Kidney InjuryCOVID-19Peritoneal DialysisAgedFemaleHumansMaleMiddle AgedNew York CityPandemicsRenal DialysisRetrospective StudiesAcute kidney injurycontinuous kidney replacement therapyCOVID-19haemodialysismortalityperitoneal dialysis

Identifiers

PMID36320182
PMCPMC10115518

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.