Evidence map›Paper›PMID 36320172›Full record

Observational studyHIV medicine2022

Increasing HIV early diagnosis by implementing an automated screening strategy in emergency departments.

Inês Vaz-Pinto, Ana Gorgulho, Catarina Esteves, Mafalda Guimarães, Vanda Castro, Alba Carrodeguas, Diogo Medina

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in HIV medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  8. Variability in Human Immunodeficiency Virus infection screening: impact of the COVID-19 pandemic.Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2025
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Inês Vaz-PintoHIV-AIDS Functional Unit, Cascais Hospital Dr. José de Almeida, Cascais, Portugal.ORCID 0000-0002-6281-8591
Ana GorgulhoHIV-AIDS Functional Unit, Cascais Hospital Dr. José de Almeida, Cascais, Portugal.ORCID 0000-0002-2031-2357
Catarina EstevesHIV-AIDS Functional Unit, Cascais Hospital Dr. José de Almeida, Cascais, Portugal.ORCID 0000-0002-4478-1318
Mafalda GuimarãesHIV-AIDS Functional Unit, Cascais Hospital Dr. José de Almeida, Cascais, Portugal.ORCID 0000-0003-1748-039X
Vanda CastroHIV-AIDS Functional Unit, Cascais Hospital Dr. José de Almeida, Cascais, Portugal.ORCID 0000-0001-9334-8353
Alba CarrodeguasGilead Sciences, Lisbon, Portugal.ORCID 0000-0001-8488-0372
Diogo MedinaGilead Sciences, Lisbon, Portugal.ORCID 0000-0001-7903-1042
Unilever (Portugal) · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLate HIV diagnosis is associated with increased morbidity, mortality and risk of onward transmission. Increasing HIV early diagnosis is still a priority. In this observational study with historical control, we determined the impact of an opportunistic HIV screening strategy in the reduction of late diagnosis and missed opportunities for earlier diagnosis.

methodsThe screening programme was implemented in the emergency department (ED) of the Hospital de Cascais between September 2018 and September 2021. Eligible patients were aged 18-64 years, with no known HIV diagnosis or antibody testing performed in the previous year, and who required blood work for any reason. Out of the 252 153 emergency visits to the ED, we identified 43 153 (17.1%) patients eligible for HIV testing. Among the total population eligible for the screening, 38 357 (88.9%) patients were ultimately tested for HIV. Impact of the ED screening was determined by analysing late diagnosis in the ED and missed opportunities at different healthcare settings 3 years before and 3 years after the start of the ED screening.

resultsAfter 3 years of automated HIV ED testing, we found 69 newly diagnosed HIV cases (54% male, 39% Portuguese nationals, mean age 40.5 years). When comparing the characteristics of HIV diagnoses made in the ED, we observed a significant reduction in the number of people with late HIV diagnosis before and after implementation of the screening programme (78.4% vs. 39.1%, respectively; p = 0.0291). The mean number of missed opportunities for diagnosis also fell (2.6 vs. 1.5 annual encounters with the healthcare system per patient, p = 0.0997).

conclusionsPeople living with HIV in Cascais and their providers miss several opportunities for earlier diagnosis. Opportunistic screening strategies in settings previously deemed to be unconventional, such as EDs, are feasible and effective in mitigating missed opportunities for timely HIV diagnosis.

Indexed as

HIV InfectionsAdultAIDS SerodiagnosisEarly DiagnosisEmergency Service, HospitalFemaleHumansMaleMass Screeningautomated screeningearly diagnosisHIVmissed opportunities

Identifiers

PMID36320172
PMCPMC10092854
OpenAlexW4307976191

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.