ArticleCerebral cortex (New York, N.Y. : 1991)2023
Default mode network scaffolds immature frontoparietal network in cognitive development.
Article in Cerebral cortex (New York, N.Y. : 1991), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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Who cites it
23 citing papers in PubMed, 42 citations in OpenAlex.
- Brain functional-structural gradient coupling reflects development, behavior and genetic influences.Nature communications · 2026Article
- Task-evoked functional connectivity exhibits novel and strengthened relationships with executive function relative to the resting state.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Acute basal ganglia ischemic stroke: a study on structure-function coupling.Brain imaging and behavior · 2026Article
- Developmental variations in recurrent spatiotemporal brain propagations from childhood to adulthood.Nature communications · 2026Article
- Brain-Computer Interface Training Enhances Attention Function via Modulating Frontoparietal Connectivity: Evidence From Functional Near-Infrared Spectroscopy.Neural plasticity · 2026Article
- Cognitive insight in patients with depression and non-suicidal self-injury.Frontiers in psychology · 2026Article
- Dynamic structure-function coupling in macroscale neonatal brain networks.Communications biology · 2025Article
- Task-evoked functional connectivity exhibits novel and strengthened relationships with executive function relative to the resting state.bioRxiv : the preprint server for biology · 2025Article
- Common and unique network basis for externally and internally driven flexibility in cognition: From a developmental perspective.Developmental cognitive neuroscience · 2025Article
- Forming Connections: Functional Brain Connectivity is Associated With Executive Functioning Abilities in Early Childhood.Developmental science · 2025Article
- Cross brain reshaping in congenital visual or hearing impairment: triple-network dysfunction.Brain communications · 2025Article
- Towards a neurodevelopmental cognitive perspective of temporal processing.Communications biology · 2024Review
- Abnormal dynamic functional connectivity and topological properties of cerebellar network in male obstructive sleep apnea.CNS neuroscience & therapeutics · 2024Article
- Population-wide cerebellar growth models of children and adolescents.Nature communications · 2024Article
- Population imaging cerebellar growth for personalized neuroscience.Nature communications · 2024Article
- Alterations of functional brain activity and connectivity in female nurses working on long-term shift.Nursing open · 2024Article
- Brain topology underlying executive functions across the lifespan: focus on the default mode network.Frontiers in psychology · 2024Article
- Static and dynamic brain functional connectivity patterns in patients with unilateral moderate-to-severe asymptomatic carotid stenosis.Frontiers in aging neuroscience · 2024Article
- Different patterns of intrinsic functional connectivity at the default mode and attentional networks predict crystalized and fluid abilities in childhood.Cerebral cortex communications · 2023Article
- Alterations in intra- and inter-network connectivity associated with cognition impairment in insulinoma patients.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
19 authors at 4 institutions in 2 countries.
Funding
Abstract
The default mode network (DMN) is a workspace for convergence of internal and external information. The frontal parietal network (FPN) is indispensable to executive functioning. Yet, how they interplay to support cognitive development remains elusive. Using longitudinal developmental fMRI with an n-back paradigm, we show a heterogeneity of maturational changes in multivoxel activity and network connectivity among DMN and FPN nodes in 528 children and 103 young adults. Compared with adults, children exhibited prominent longitudinal improvement but still inferior behavioral performance, which paired with less pronounced DMN deactivation and weaker FPN activation in children, but stronger DMN coupling with FPN regions. Children's DMN reached an adult-like level earlier than FPN at both multivoxel activity pattern and intranetwork connectivity levels. Intrinsic DMN-FPN internetwork coupling in children mediated the relationship between age and working memory-related functional coupling of these networks, with posterior cingulate cortex (PCC)-dorsolateral prefrontal cortex (DLPFC) coupling emerging as most prominent pathway. Coupling of PCC-DLPFC may further work together with task-invoked activity in PCC to account for longitudinal improvement in behavioral performance in children. Our findings suggest that the DMN provides a scaffolding effect in support of an immature FPN that is critical for the development of executive functions in children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.