Evidence map›Paper›PMID 36320113›Full record

ArticleThe Korean journal of parasitology2022

Excretory-Secretory Products of Trichomonas vaginalis Cause Apoptosis in Mouse Sperm in Vitro.

Jihyun Keum, Jaesook Roh, Jae-Sook Ryu, Ki-Young Ryu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Korean journal of parasitology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jihyun KeumDeptartment of Obstetrics & Gynecology, College of Medicine, Hanyang University, Seoul 04763, Korea.
Jaesook RohLaboratory of Reproductive Endocrinology, Deptartment. of Anatomy & Cell Biology, College of Medicine, Hanyang University, Seoul 04763, Korea.
Jae-Sook RyuDepartment of Environmental Biology & Medical Parasitology, College of Medicine, Hanyang University, Seoul 04763, Korea.
Ki-Young RyuDepartment of Obstetrics & Gynecology, College of Medicine, Hanyang University, Guri 11923, Korea.
Hanyang University · KRHanyang University Guri Hospital · KRHanyang University Medical Center · KR

Funding

Hanyang University HY-2017
6 · The paper itself

Abstract

Excretory-secretory products (ESP) of T. vaginalis have been shown to inhibit sperm motility, viability, and functional integrity, leading to a decreased fertilization rate in vitro. This study investigated whether T. vaginalis induce apoptosis and ultrastructural changes of sperm using flow cytometry and electron microscopy. Incubation of sperm with T. vaginalis ESP increased phosphatidylserine externalization and DNA fragmentation, and decreased mitochondrial membrane potential. Transmission electron microscopy of sperm incubated with ESP revealed abnormal features such as distorted heads, broken necks, and acrosomes exocytosis. This is the first report that demonstrates a direct impact of T. vaginalis ESP on sperm apoptosis and architecture in vitro.

Indexed as

Trichomonas vaginalisAnimalsApoptosisMaleMiceSemenSpermatozoaSperm Motilityapoptosisexcretory-secretory productsspermTrichomonas vaginalis

Identifiers

PMID36320113
PMCPMC9633159
OpenAlexW4307947506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.