Evidence map›Paper›PMID 36320045›Full record

SynthesisWorld journal of emergency surgery : WJES2022

The outcomes of right-sided and left-sided colonic diverticulitis following non-operative management: a systematic review and meta-analysis.

Sih-Shiang Huang, Chih-Wei Sung, Hsiu-Po Wang, Wan-Ching Lien

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in World journal of emergency surgery : WJES, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06153030 (Unexpected Diagnosis in Right Lower Quadrant Pain), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06153030 completednot on this map

Unexpected Diagnosis in Right Lower Quadrant Pain: Right Colon Diverticulitis

Typeobservational_patient_registrySponsorHaydarpasa Numune Training and Research HospitalRan2018 to 2023Enrolled20ConditionsDiverticulitis, ColonicArmsno intervention
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sih-Shiang HuangDepartment of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Chih-Wei SungDepartment of Emergency Medicine, National Taiwan University Hsin-Chu Hospital, Hsinchu City, Taiwan.
Hsiu-Po WangDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Wan-Ching LienDepartment of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan. wanchinglien@ntu.edu.tw.
National Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is no sufficient overview of outcomes in right-sided and left-sided colonic diverticulitis (CD) following non-operative management. This systematic review was conducted to evaluate the recurrence/treatment failure in right-sided and left-sided CD.

methodsA systematic review was conducted following PRISMA guidelines. MEDLINE, Embase, and Cochrane Library from inception to Dec 2021 were searched. The study characteristics, recurrence/treatment failure, and risk factors for recurrence/treatment failure were extracted. Proportional meta-analyses were performed to calculate the pooled recurrent/treatment failure rate of right-sided and left-sided CD using the random effect model. Logistic regression was applied for the factors associated with the recurrence/treatment failure.

resultsThirty-eight studies with 10,129 patients were included, and only two studies comprised both sides of CD. None of the studies had a high risk of bias although significant heterogeneity existed. The pooled recurrence rate was 10% (95% CI 8-13%, I

conclusionNon-operative management is effective with low rates of recurrence and treatment failure for both right-sided and left-sided CD although left-sided exhibits a higher recurrence. The recurrence rates did not differ between patients receiving antibiotics or not in uncomplicated CD. Age and sex were not associated with the recurrence although other risk factors were dispersing. Further risk factors for recurrence and treatment failure would be investigated for precise clinical decision-making and individualized strategy.

Indexed as

Diverticulitis, ColonicAnti-Bacterial AgentsHumansRisk FactorsAnti-Bacterial AgentsColonic diverticulitisLeft-sidedNon-operative managementRecurrenceRight-sidedTreatment failure

Identifiers

PMID36320045
PMCPMC9628071
OpenAlexW4308019798

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.