Evidence map›Paper›PMID 36320021›Full record

ArticleBMC public health2022

Sleep disturbance is associated with mild cognitive impairment: a community population-based cross-sectional study.

Fan Gao, Shan Wei, Liangjun Dang, Yao Gao, Ling Gao, Suhang Shang, Chen Chen, Kang Huo, Jingyi Wang, Jin Wang and 1 more

Abstract read
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fan GaoDepartment of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Rd, 710061, Xi'an, China.
Shan WeiDepartment of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Rd, 710061, Xi'an, China.
Liangjun DangDepartment of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Rd, 710061, Xi'an, China.
Yao GaoDepartment of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Rd, 710061, Xi'an, China.
Ling GaoDepartment of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Rd, 710061, Xi'an, China.
Suhang ShangDepartment of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Rd, 710061, Xi'an, China.
Chen ChenDepartment of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Rd, 710061, Xi'an, China.
Kang HuoDepartment of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Rd, 710061, Xi'an, China.
Jingyi WangHuyi Hospital of Traditional Chinese Medicine, Xi'an, China.
Jin WangDepartment of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Rd, 710061, Xi'an, China. drwangjin@163.com.
Qiumin QuDepartment of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Rd, 710061, Xi'an, China. quqiumin@xjtufh.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSleep is conducive to the elimination of brain metabolites and the recovery of brain function. However, the relationship between sleep disturbance and Mild Cognitive Impairment is not fully been determined.

methodsThis was a community population-based cross-sectional study. A total of 1,443 participants from a village in the suburbs of Xi'an, China were enrolled in 2017. Sleep quality was evaluated using the Pittsburgh sleep quality index (PSQI), and sleep disturbance was defined as a PSQI score > 5. Mini-Mental State Examination (MMSE) was used to assess cognitive function and Mild Cognitive Impairment(MCI) was defined as the MMSE score less than cutoff values and meets the diagnostic criteria. Univariate and multivariate analyses were used to analyze the relationships between sleep disturbance and MCI.

resultsAmong 1,443 subjects, 69(4.78%) had MCI, and 830 (57.52%) had sleep disturbance. In bivariate analysis, MCI was associated with sleep disturbance (ρ = 0.094, P<0.001). In the binary logistic regression, MCI was positively associated with the sleep disturbance (OR = 2.027, 95%CI = 1.112-3.698, P = 0.021). In the internal constitution of PSQI, MCI was negatively associated with the habitual sleep efficiency (OR = 0.447, 95%CI = 0.299-0.669, P < 0.001). Compared with waking up before or at 7 am, waking up after 7 am (OR = 0.555, 95%CI = 0.309-0.995, P = 0.048), or 8 am (OR = 0.296, 95%CI = 0.097-0.902, P = 0.032) was probably more likely to have normal cognition. However, people who slept more than 8 h a day might be more likely to suffer from MCI (OR = 5.560, 95%CI = 1.419-21.789, P = 0.014).

conclusionSleep disturbance is associated with Mild Cognitive Impairment. However, the causal relationship between them is not clear. It needs to be further studied.

Indexed as

Cognitive DysfunctionSleep Wake DisordersCognitionCross-Sectional StudiesHumansSleepCross-sectional studyMild cognitive impairmentRisk factorSleep disturbance

Identifiers

PMID36320021
PMCPMC9624002

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.