Evidence map›Paper›PMID 36319987›Full record

ArticleBMC cancer2022

Paradoxes of breast cancer incidence and mortality in two corners of Europe.

Mikaela Roginski, Dimitra Sifaki-Pistolla, Andreas Stomby, Georgia Velivasaki, Tomas Faresjö, Christos Lionis, Åshild Faresjö

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06471452 (To Live Better After Breast Cancer Treatment - a Randomized Pilot Trial of a Supportive and Person-centered Care Intervention in Primary Healthcare), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06471452 naunknown statusnot on this mapstarted 2023, after this paper: background citation

To Live Better After Breast Cancer Treatment - a Randomized Pilot Trial of a Supportive and Person-centered Care Intervention in Primary Healthcare

TypeinterventionalSponsorKarolinska InstitutetRan2023 to 2025Enrolled40ConditionsBreast Cancer SurvivorshipArmsInteraktor
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
  4. Article
  5. Review
  6. Article
  7. Trends in breast cancer mortality in Mexican women.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mikaela RoginskiDepartment of Health, Medicine and Caring Sciences, Linköping University, SE-581 83, Linköping, Sweden. Mikaela.roginski@liu.se.
Dimitra Sifaki-PistollaClinic of Social and Family Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece.
Andreas StombyDepartment of Health, Medicine and Caring Sciences, Linköping University, SE-581 83, Linköping, Sweden.
Georgia VelivasakiClinic of Social and Family Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece.
Tomas FaresjöDepartment of Health, Medicine and Caring Sciences, Linköping University, SE-581 83, Linköping, Sweden.
Christos LionisDepartment of Health, Medicine and Caring Sciences, Linköping University, SE-581 83, Linköping, Sweden.
Åshild FaresjöDepartment of Health, Medicine and Caring Sciences, Linköping University, SE-581 83, Linköping, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer incidence is rising globally, while mortality rates show a geographical heterogenous pattern. Early detection and treatment have been proven to have a profound impact on breast cancer prognosis. The aim of his study was to compare breast cancer incidence, mortality, and survival rates in two contrasting corners of Europe, Sweden and Crete, to better understand cancer determinants with focus on disease burden and sociocultural factors.

methodsBreast cancer data from Sweden and Crete was derived from registries. Incidence and mortality were expressed as Age-Standardized Incidence Rates (ASIR), Age-Standardized Mortality Rates (ASMR).

findingsBreast cancer incidence has for decades risen in Sweden and on Crete. In 2019, ASIR was 217.5 in Sweden and 58.9 on Crete, (p < 0.001). Mortality rates showed opposite trends. ASMR in Sweden was reduced from 25.5 to 16.8 (2005-2019) while on Crete, ASMR increased from 22.1 to 25.3. A successive rise in survival rate in Sweden with a 5-year survival rate of 92% since 2015, but a converse development on Crete with 85% 5-year survival rate the same year.

interpretationThe incidence of breast cancer is slowly rising in both studied regions, but mortality increases on Crete in contrast to Sweden with sinking mortality rates. The interpretation of these findings is that differences in health care systems and health policies including differences in early detection like screening programs and early treatment, as well as sociocultural factors in the two countries might play an important role on the differences found in breast cancer burden.

Indexed as

Breast NeoplasmsFemaleGreeceHumansIncidenceMortalityRegistriesSurvival RateSwedenBreast cancerComparative studyIncidenceMortalityRegister data

Identifiers

PMID36319987
PMCPMC9628067

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.