ArticleBMC geriatrics2022
Contributions of early-life cognitive reserve and late-life leisure activity to successful and pathological cognitive aging.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Defining exceptional cognition in older adults: A systematic review of cognitive super-ageing.International journal of geriatric psychiatry · 2023Pooled it
- Three-Year Changes in Cognitive and Brain Functions Among Community-Dwelling Older Adults Who Continue Working.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2026Article
- Associations of cognitive activity and access to resources with cognitive decline in a broad representation of older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Identifying individuals at risk of cognitive decline: cross-sectional analysis of variability in neuropsychological test scores among community-dwelling older adults.BMC public health · 2026Article
- Cross-cultural adaptation and psychometric evaluation of the Chinese version of the short version of the Cognitive Reserve Index Questionnaire (s-CRIq): a cross-sectional study.BMC psychiatry · 2026Article
- The Contribution of Cognitive Reserve to Mental Health Against Adversarial Life Events in a Large Cross-Sectional Sample of Japanese People.The Psychiatric quarterly · 2026Article
- Do cognitive reserve proxies capture a common neural signature? A systematic review and meta-analysis of task-based fMRI studies.Psychoradiology · 2026Review
- The "Dark Side" of Pre-Retirement Work Attachment for Later-Life Mental Health: Mediating Role of Retirement Adjustment and Moderating Role of Social Network.Psychology research and behavior management · 2026Article
- Experiential factors mediate the link between brain status and theory of mind in building-up cognitive reserve.Scientific reports · 2025Article
- Risk prediction for elderly cognitive impairment by radiomic and morphological quantification analysis based on a cerebral MRA imaging cohort.European radiology · 2025Article
- The role of elevated depressive symptoms in the incident mild cognitive impairment in China: a 9-year prospective cohort study of middle-aged and older Chinese adults (2011-2020).Frontiers in psychiatry · 2025Article
- Association of education level and depression with cognitive decline: findings from the examining cognitive health outcomes in heart failure study.Frontiers in cardiovascular medicine · 2025Article
- Cognitive resilience/reserve: Myth or reality? A review of definitions and measurement methods.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Review
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6 authors.
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Abstract
backgroundThe identification of factors that specifically influence pathological and successful cognitive aging is a prerequisite for implementing disease prevention and promoting successful aging. However, multi-domain behavioral factors that characterize the difference between successful and pathological cognitive aging are not clear yet.
methodsA group of community-dwelling older adults (N = 1347, aged 70-88 years) in Beijing was recruited in this cross-sectional study, and a sub-cohort was further divided into successful cognitive aging (SCA, N = 154), mild cognitive impairment (MCI, N = 256), and cognitively normal control (CNC, N = 173) groups. Analyses of variance, regression models with the Shapley value algorithm, and structural equation model (SEM) analyses were conducted to determine specific influencing factors and to evaluate their relative importance and interacting relationships in altering cognitive performance.
resultsWe found that abundant early-life cognitive reserve (ECR, including the level of education and occupational attainment) and reduced late-life leisure activity (LLA, including mental, physical, and social activities) were distinct characteristics of SCA and MCI, respectively. The level of education, age, mental activity, and occupational attainment were the top four important factors that explained 31.6% of cognitive variability. By SEM analyses, we firstly found that LLA partially mediated the relationship between ECR and cognition; and further multi-group SEM analyses showed ECR played a more direct role in the SCA group than in the MCI group: in the SCA group, only the direct effect of ECR on cognition was significant, and in the MCI group, direct effects between ECR, LLA and cognition were all significant.
conclusionsResults of this large-sample community-based study suggest it is important for older adults to have an abundant ECR for SCA, and to keep a high level of LLA to prevent cognitive impairment. This study clarifies the important rankings of behavioral characteristics of cognitive aging, and the relationship that ECR has a long-lasting effect on LLA and finally on cognition, providing efficient guidance for older adults to improve their cognitive function and new evidence to explain the heterogeneity of cognitive aging.
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