ArticleScientific reports2022
Validation of days alive and out of hospital as a new patient-centered outcome to quantify life impact after heart transplantation.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Comparative analysis of postoperative outcomes and utilization trends for valve-in-valve transcatheter aortic valve implantation versus reoperative surgical aortic valve replacement.Journal of cardiothoracic surgery · 2026Article
- Evaluation of days alive out of hospital as an outcome after intensive care admission: a national retrospective cohort study.Critical care (London, England) · 2026Article
- Pre-Transplant Diagnosis Asserts Significant Post-Transplant Burden on Readmissions and Reinterventions: A Multicenter Study.Pediatric transplantation · 2025Article
- Days alive and out of the hospital at 1 year following heart transplant: Comparing donation after brain death versus after circulatory death.JHLT open · 2025Article
- Advancing patient-centered metrics for heart transplantation: The role of days alive and outside the hospital.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2025Article
- Days at home after surgery as a perioperative outcome: scoping review and recommendations for use in health services research.The British journal of surgery · 2024Article
- The Association Between Preoperative Pectoralis Muscle Quantity and Outcomes After Cardiac Transplantation.Journal of cardiac failure · 2024Article
- Days alive and out of hospital for children born with single-ventricle heart disease.Cardiology in the young · 2024Article
- Association between early postoperative hypoalbuminaemia and outcome after orthotopic heart transplantation.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The number of patients waiting for heart transplantation (HTX) is increasing. Thus, identification of outcome-relevant factors is crucial. This study aimed to identify perioperative factors associated with days alive and out of hospital (DAOH)-a patient-centered outcome to quantify life impact-after HTX. This retrospective cohort study screened 187 patients who underwent HTX at university hospital Duesseldorf, Germany from September 2010 to December 2020. The primary endpoint was DAOH at 1 year. Risk factors for mortality after HTX were assessed in univariate analysis. Variables with significant association were entered into multivariable quantile regression. In total, 175 patients were included into analysis. Median DAOH at 1 year was 295 (223-322) days. In univariate analysis the following variables were associated with reduced DAOH: recipient or donor diabetes pre-HTX, renal replacement therapy (RRT), VA-ECMO therapy, recipient body mass index, recipient estimated glomerular filtration rate (eGFR) and postoperative duration of mechanical ventilation. After adjustment, mechanical ventilation, RRT, eGFR and recipient diabetes showed significant independent association with DAOH. This study identified risk factors associated with reduced DAOH at 1-year after HTX. These findings might complement existing data for outcome of patients undergoing HTX.
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