Evidence map›Paper›PMID 36319769›Full record

ArticleInternational archives of occupational and environmental health2023

Circulatory system disease mortality and occupational exposure to radon progeny in the cohort of Newfoundland Fluorspar Miners between 1950 and 2016.

Paul J Villeneuve, Howard I Morrison, Karena Volesky, Rachel S D Lane

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International archives of occupational and environmental health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Paul J VilleneuveDepartment of Neuroscience, Faculty of Science, Carleton University, Health Sciences Building, Room 6307, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada. Paul.Villeneuve@carleton.ca.ORCID 0000-0001-7786-7997
Howard I MorrisonCentre for Surveillance and Applied Research, Public Health Agency of Canada, Ottawa, ON, Canada.
Karena VoleskyMcGill University, Montreal, QC, Canada.
Rachel S D LaneCanadian Nuclear Safety Commission, Ottawa, Canada.
Canadian Nuclear Safety Commission · CACarleton University · CAMcGill University · CAPublic Health Agency of Canada · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesExposure to ionizing radiation may increase the risk of circulatory diseases, including heart disease. A limited number of cohort studies of underground miners have investigated these associations. We previously reported a positive but non-statistically significant association between radon progeny and heart disease in a cohort of Newfoundland fluorspar miners. In this study, we report updated findings that incorporate 15 additional years of follow-up.

methodsThe cohort included 2050 miners who worked in the fluorspar mines from 1933 to 1978. Statistics Canada linked the personal identifying data of the miners to Canadian mortality data to identify deaths from 1950 to 2016. We used previously derived individual-level estimates of annual radon progeny exposure in working-level months. Cumulative exposure was categorized into quantiles. We estimated relative risks and their 95% confidence intervals using Poisson regression for deaths from circulatory, ischemic heart disease and acute myocardial infarction. Relative risks were adjusted for attained age, calendar year, and the average number of cigarettes smoked daily.

resultsRelative to the Newfoundland male population, the standardized mortality ratio for circulatory disease in this cohort was 0.82 (95% CI 0.74-0.91). Those in the highest quantile of cumulative radon progeny exposure had a relative risk of circulatory disease mortality of 1.03 (95% CI 0.76-1.40) compared to those in the lowest quantile. The corresponding estimates for ischemic disease and acute myocardial infarction were 0.99 (95% CI 0.66-1.48), and 1.39 (95% CI 0.84-2.30), respectively.

conclusionsOur findings do not support the hypothesis that occupational exposure to radon progeny increases the risk of circulatory disease.

Indexed as

Cardiovascular DiseasesHeart DiseasesLung NeoplasmsMyocardial InfarctionNeoplasms, Radiation-InducedOccupational DiseasesOccupational ExposureRadonUraniumCanadaHumansMaleNewfoundland and LabradorRadon DaughtersRadonRadon DaughtersUraniumCardiovascular diseaseCohort studyMinerRadon progeny

Identifiers

PMID36319769
PMCPMC9968242
OpenAlexW4307806265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.