Evidence map›Paper›PMID 36319757›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2023

Pregnancies complicated by gestational diabetes and fetal growth restriction: an analysis of maternal and fetal body composition using magnetic resonance imaging.

Katie M Strobel, Sevgi Gokce Kafali, Shu-Fu Shih, Alexandra M Artura, Rinat Masamed, David Elashoff, Holden H Wu, Kara L Calkins

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Free-breathing MRI techniques for fat and RMagma (New York, N.Y.) · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Katie M StrobelDepartment of Pediatrics, Division of Neonatology & Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-7717-0425
Sevgi Gokce KafaliDepartment of Radiological Sciences, University of California Los Angeles, Los Angeles, CA, USA.
Shu-Fu ShihDepartment of Radiological Sciences, University of California Los Angeles, Los Angeles, CA, USA.
Alexandra M ArturaUniversity of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0001-6322-1554
Rinat MasamedDepartment of Radiological Sciences, University of California Los Angeles, Los Angeles, CA, USA.
David ElashoffDepartment of Medicine, Biostatistics and Computational Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Holden H WuDepartment of Radiological Sciences, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-2585-5916
Kara L CalkinsDepartment of Pediatrics, Division of Neonatology & Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA. kcalkins@mednet.ucla.edu.ORCID 0000-0001-6658-7981
University of California, Los Angeles · US

Funding

Quantifying Body Composition and Liver Disease in Children using Free-Breathing MRI and MRER01DK124417 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CALKINS, KARA LYNNE, WU, HOLDEN H · 2020 to 2023
$2.3M
NIDDK NIH HHS R01-124417-01NIDDK NIH HHS R01 DK124417
6 · The paper itself

Abstract

introductionMaternal body composition may influence fetal body composition.

objectiveThe objective of this pilot study was to investigate the relationship between maternal and fetal body composition.

methodsThree pregnant women cohorts were studied: healthy, gestational diabetes (GDM), and fetal growth restriction (FGR). Maternal body composition (visceral adipose tissue volume (VAT), subcutaneous adipose tissue volume (SAT), pancreatic and hepatic proton-density fat fraction (PDFF) and fetal body composition (abdominal SAT and hepatic PDFF) were measured using MRI between 30 to 36 weeks gestation.

resultsCompared to healthy and FGR fetuses, GDM fetuses had greater hepatic PDFF (5.2 [4.2, 5.5]% vs. 3.2 [3, 3.3]% vs. 1.9 [1.4, 3.7]%, p = 0.004). Fetal hepatic PDFF was associated with maternal SAT (r = 0.47, p = 0.02), VAT (r = 0.62, p = 0.002), and pancreatic PDFF (r = 0.54, p = 0.008). When controlling for maternal SAT, GDM increased fetal hepatic PDFF by 0.9 ([0.51, 1.3], p = 0.001).

conclusionIn this study, maternal SAT, VAT, and GDM status were positively associated with fetal hepatic PDFF.

Indexed as

Diabetes, GestationalAdipose TissueBody CompositionFemaleFetal Growth RetardationFetusHumansMagnetic Resonance ImagingPilot ProjectsPregnancy

Identifiers

PMID36319757
PMCPMC9840659
OpenAlexW4307968861

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.