Evidence map›Paper›PMID 36319588›Full record

ArticleEuropean journal of haematology2023

Outcomes of coronavirus disease 2019 (COVID-19) and risk factors associated with severe COVID-19 in patients with mature B-cell non-Hodgkin lymphomas: A US electronic health record cohort study.

Xiaomeng Yue, David Hallett, Yangyang Liu, Elisa Basa, Annie McNeill, James P Dean

Open access · hybridAbstract read
In one paragraph

Article in European journal of haematology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaomeng YueAbbVie, Inc., North Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-4418-7079
David HallettAbbVie, Inc., North Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-6808-4157
Yangyang LiuAbbVie, Inc., North Chicago, Illinois, USA.
Elisa BasaAbbVie, Inc., North Chicago, Illinois, USA.
Annie McNeillAbbVie, Inc., North Chicago, Illinois, USA.
James P DeanPharmacyclics LLC, an AbbVie Company, South San Francisco, California, USA.ORCID https://orcid.org/0000-0001-8058-1682
AbbVie (United States) · US

Funding

Pharmacyclics LLC, an AbbVie Company
6 · The paper itself

Abstract

objectivesThe objectives of this study were to assess the risk of severe coronavirus disease 2019 (COVID-19) outcomes in patients with mature B-cell non-Hodgkin lymphoma (mature B-cell NHL) compared with other cancers and to identify risk factors associated with severe COVID-19.

methodsThis study used Optum's electronic health record database. Risk factors were evaluated using multivariable logistic regression.

resultsPatients with mature B-cell NHL were more likely to be hospitalized or die from COVID-19 (age- and sex-standardized risk: 15.6%, 2.1%, respectively) than those without cancer (9.5%, 1.2%), or with solid tumors (9.7%, 1.3%). In patients with mature B-cell NHL, factors associated with severe COVID-19 outcomes included: greater age (75-84 years, adjusted odds ratio, 1.6 [95% CI, 1.3-2.0]; ≥85, 2.6 [2.0-3.4]), male sex (1.4 [1.2-1.6]), chronic kidney disease (1.4 [1.1-1.7]), chronic obstructive pulmonary disease (1.3 [1.0-1.6]), type 2 diabetes (1.3 [1.1-1.5]), and receiving treatment for NHL (1.5 [1.1-2.1]).

conclusionsThese data suggest that patients with mature B-cell NHL are at a higher risk of severe COVID-19 than patients with solid tumors or without cancer and that risk factors are largely consistent with those in the general population.

Indexed as

COVID-19Diabetes Mellitus, Type 2Lymphoma, Non-HodgkinNeoplasmsAgedAged, 80 and overCohort StudiesElectronic Health RecordsHumansMaleRisk FactorsCOVID-19epidemiologyhematologyhospitalizationlymphomamortalityneoplasmsobservational study

Identifiers

PMID36319588
PMCPMC9877844
OpenAlexW4307831344

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.