Evidence map›Paper›PMID 36319061›Full record

ArticleBMJ open2022

Matthew F Mart, Matthew W Semler, Gordon Bernard, Jonathan D Casey, E Wesley Ely, Robert Freundlich, James C Jackson, Amy Kiehl, Cathy Jenkins, Guanchao Wang and 8 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Oxygen-Saturation Targets and Cognitive and Functional Outcomes in Mechanically Ventilated Adults.American journal of respiratory and critical care medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Matthew F MartDepartment of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA matthew.f.mart@vumc.org.ORCID 0000-0002-6727-8838
Matthew W SemlerDepartment of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-7664-8263
Gordon BernardDepartment of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Jonathan D CaseyDepartment of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
E Wesley ElyDepartment of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Robert FreundlichDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-0343-9823
James C JacksonDepartment of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Amy KiehlCritical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Cathy JenkinsDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Guanchao WangDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Christopher LindsellDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Patsy BryantCritical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Todd W RiceDepartment of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Wesley H SelfVanderbilt Institute for Clinical and Translational Research (VICTR), Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Joanna StollingsCritical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Jonathan P WandererDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Li WangDepartment of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Jin Ho HanCritical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Vanderbilt University Medical Center · USVA Tennessee Valley Healthcare System · USPulmonary and Allergy Associates · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Clinical and Translational Training Program in Pulmonary MedicineT32HL087738 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lorraine B Ware · 2007 to 2026
$7.0M
Bag-Mask Ventilation to PreVent Hypoxemia during Tracheal Intubation in the Emergency Department: A Clinical TrialK23HL153584 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASEY, JONATHAN DALE · 2020 to 2024
$900k
Reducing Reintubation Risk in High-Risk Cardiac Surgery Patients with High-Flow Nasal Cannula -the "I-CAN" studyK23HL148640 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI FREUNDLICH, ROBERT EDWARD · 2020 to 2024
$867k
Cognitive Outcomes in the Pragmatic Investigation of Optimal Oxygen Targets (CO-PILOT) TrialR21AG063126 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HAN, JIN HO · 2020 to 2021
$468k
NCATS NIH HHS UL1 TR000445NHLBI NIH HHS K23 HL148640NHLBI NIH HHS K23 HL153584NHLBI NIH HHS T32 HL087738NIA NIH HHS R21 AG063126
6 · The paper itself

Abstract

introductionLong-term cognitive impairment is one of the most common complications of critical illness among survivors who receive mechanical ventilation. Recommended oxygen targets during mechanical ventilation vary among international guidelines. Different oxygen targets during mechanical ventilation have the potential to alter long-term cognitive function due to cerebral hypoxemia or hyperoxemia. Whether higher, intermediate or lower SpO METHODS AND ANALYSIS: The ETHICS AND DISSEMINATION: The CO-PILOT ancillary study was approved by the Vanderbilt Institutional Review Board. The results will be submitted for publication in a peer-reviewed journal and presented at one or more scientific conferences.

Indexed as

Critical IllnessCognitionHumansOxygenPragmatic Clinical Trials as TopicQuality of LifeRandomized Controlled Trials as TopicOxygenadult intensive & critical caredelirium & cognitive disordersstatistics & research methods

Identifiers

PMID36319061
PMCPMC9628689
OpenAlexW4308016895

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.