ArticleBMJ open2022
Association of sleep behaviour and pattern with the risk of glaucoma: a prospective cohort study in the UK Biobank.
Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 21 citations in OpenAlex.
- Adrenergic Pathways Mediate Circadian IOP Rhythm in Rats.Investigative ophthalmology & visual science · 2026Article
- Assessing physical activity and sleep patterns in glaucoma using wearable devices.The British journal of ophthalmology · 2026Article
- Sleep Pattern and Structural Damage in Older Adults with Glaucoma: A United States and China Study.Ophthalmology science · 2026Article
- Intrinsic Capacity, Polygenic Risk Score, and Risk of Glaucoma.Translational vision science & technology · 2026Article
- Article
- Circadian IOP Rhythm in Rats Is Driven by Neural Signals From the Brain.Investigative ophthalmology & visual science · 2026Article
- Associations between the Mediterranean lifestyle and incident age-related eye diseases: a longitudinal analysis from the UK Biobank.Journal of global health · 2026Article
- Association Between Chronic Pain and Risk of Glaucoma: A Prospective Cohort Study.Translational vision science & technology · 2025Article
- Association Between Eye Diseases and Sleep Duration: A Nationwide Cross-Sectional Study.Psychiatry investigation · 2025Article
- Sleep and mood in central serous chorioretinopathy.Eye (London, England) · 2025Article
- Sleep duration modifies the association between obstructive sleep apnea risk and glaucoma: evidence from the Korea National Health and Nutrition Examination Survey.Eye and vision (London, England) · 2025Article
- LLM-based multi-agent system for neuro-ophthalmic diagnosis and personalized treatment planning.Frontiers in neuroscience · 2025Article
- Exploring the Link Between Sleep Duration and Visual Impairment and Major Eye Diseases: National Health and Nutrition Examination Survey 2005-2008.BioMed research international · 2025Article
- Sleep-disordered breathing and metabolic syndrome across gender, age, and sleep subtypes in East Asians.Frontiers in endocrinology · 2025Article
- Evaluation of Reporting Quality of Glaucoma Randomized Controlled Trial Abstracts: Current Status and Future Perspectives.Life (Basel, Switzerland) · 2024Article
- Mendelian randomization study shows no causal relationship between psychiatric disorders and glaucoma in European and East Asian populations.Frontiers in genetics · 2024Article
- Investigating the Causal Relationship Between Sleep Behaviors and Primary Open-Angle Glaucoma: A Bidirectional Two-Sample Mendelian Randomization Study.Nature and science of sleep · 2024Article
- The Potential Effects of Light Irradiance in Glaucoma and Photobiomodulation Therapy.Bioengineering (Basel, Switzerland) · 2023Review
- Glaucoma After Dark: Sleep, Circadian Stress, and Unmeasured Drivers of Disease.Journal of current glaucoma practiceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 4 countries.
Funding
Abstract
objectivesGiven the role of intraocular pressure in glaucoma, the patient's sleeping pattern might contribute to the development and progression of glaucoma. We performed a study to understand the association between sleep behaviours and glaucoma.
designOur study was a prospective cohort study.
settingThis was a prospective cohort study in the UK Biobank. Self-reported data on five sleep behaviours were collected using a questionnaire at baseline. We identified four sleep patterns based on a cluster analysis of the sleep behaviours.
participantsIn the UK Biobank, 409 053 participants were recruited between 2006 and 2010 and followed for a diagnosis of glaucoma. We identified glaucoma as any hospital admission with a diagnosis of glaucoma, based on UK Biobank inpatient hospital data. Individuals who withdrew from the UK Biobank, or were diagnosed with glaucoma before recruitment, or had self-reported surgery or laser treatment for glaucoma, or had no information on sleep behaviors were excluded. PRIMARY AND SECONDARY OUTCOME MEASURES: We estimated hazard ratios (HRs) with 95% confidence intervals (CI) using Cox proportional hazards models to estimate the associations of different sleep behaviors, as well as identified sleep patterns, with the risk of glaucoma, adjusting for multiple confounders.
resultsCompared with individuals who had a healthy sleep pattern, an excess risk of any glaucoma was observed among individuals with snoring and daytime sleepiness (HR 1.11, 95% CI 1.03 to 1.19) or insomnia and short/long sleep duration (HR 1.13, 95% CI 1.06 to 1.20), but not late chronotype sleep pattern (HR 0.98, 95% CI 0.93 to 1.03).
conclusionSnoring, daytime sleepiness, insomnia, and short/long duration, individually or jointly, were all associated with the risk of glaucoma. These findings underscore the need for sleep intervention for individuals at high risk of glaucoma as well as potential ophthalmologic screening among individuals with chronic sleep problems for glaucoma prevention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.