Evidence map›Paper›PMID 36319035›Full record

ArticleBMJ case reports2022

Rituximab for steroid-resistant organising pneumonia in a woman with rheumatoid arthritis.

Christine Elizabeth Loftis, Emilia Dulgheru, Adolfo Kaplan

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christine Elizabeth LoftisInternal Medicine, The University of Texas Rio Grande Valley School of Medicine, Edinburg, Texas, USA Christine.Loftis01@utrgv.edu.ORCID http://orcid.org/0000-0001-6597-7996
Emilia DulgheruRheumatology Institute at Doctors Hospital at Renaissance, Edinburg, Texas, USA.
Adolfo KaplanPulmonary and Sleep Center of the Valley, McAllen, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organising pneumonia (OP) is a form of interstitial pneumonia characterised by inflammation and scarring leading to obstruction within the small airways and alveoli. Practice guidelines recommend treatment of moderate to severe OP with glucocorticoids; however, there have been cases of steroid-resistant OP successfully treated with rituximab. We describe a case of a woman in her 20s with rheumatoid arthritis who presented with pleuritic chest pain, haemoptysis and dyspnoea on exertion and was diagnosed with OP after multiple radiographic images and biopsies. The patient failed numerous treatment regimens, including corticosteroids, antibiotics and mycophenolate, but was successfully treated with rituximab. This case highlights the importance of identifying new therapeutic agents that will minimise the use of glucocorticoids in the treatment of OP.

Indexed as

Arthritis, RheumatoidCryptogenic Organizing PneumoniaPneumoniaFemaleGlucocorticoidsHumansRituximabSteroidsGlucocorticoidsRituximabSteroidsConnective tissue diseaseMusculoskeletal and joint disordersPleural infectionPneumonia (respiratory medicine)Rheumatoid arthritis

Identifiers

PMID36319035
PMCPMC9628664

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.