Evidence map›Paper›PMID 36318811›Full record

ReviewZebrafish2022

A Simple Method for Inducing Masculinization of Zebrafish Stocks Using 17α-Methyltestosterone.

Jennifer L Matthews, Joy Murphy, Andrzej Nasiadka, Zoltan M Varga

Abstract readReview
In one paragraph

Review in Zebrafish, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jennifer L MatthewsZebrafish International Resource Center, University of Oregon, Eugene, Oregon, USA.
Joy MurphyZebrafish International Resource Center, University of Oregon, Eugene, Oregon, USA.
Andrzej NasiadkaZebrafish International Resource Center, University of Oregon, Eugene, Oregon, USA.
Zoltan M VargaZebrafish International Resource Center, University of Oregon, Eugene, Oregon, USA.

Funding

Zebrafish International Resource Center (ZIRC)P40OD011021 · OD · UNIVERSITY OF OREGON · PI Zoltan Marton Varga · 2012 to 2026
$36.0M
NIH HHS P40 OD011021
6 · The paper itself

Abstract

Severely skewed sex ratios in zebrafish stocks can pose significant hurdles for line propagation and sperm cryopreservation. To overcome female-biased sex ratios in stocks derived from imported sperm samples, the Zebrafish International Resource Center has implemented routine supplementation of larval food with 17α-methyltestosterone to skew gonadal sex differentiation toward masculinization. Resulting stocks averaged 80% males.

Indexed as

MethyltestosteroneZebrafishAnimalsFemaleGonadsMaleSemenSex DifferentiationMethyltestosteroneDanio reriogonad differentiationhormone treatmenthusbandrysex determinationsynthetic androgen

Identifiers

PMID36318811
PMCPMC9810344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.