Evidence map›Paper›PMID 36318523›Full record

ArticlePloS one2022

Optimal utilization of prevention of mother-to-child transmission of HIV services among adolescents under group versus focused antenatal care in Eastern Uganda.

Rebecca Akunzirwe, Sabrina Bakeera-Kitaka, Joan N Kalyango, Jane Frances Zalwango, Judith Amutuhaire Ssemasaazi, Tom Okello, Remmy Buhuguru, Sarah Kiguli, Aloysius G Mubuuke, Sam Ononge

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Rebecca AkunzirweClinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID 0000-0001-7191-4318
Sabrina Bakeera-KitakaDepartment of Pediatrics and Child Health College of Health Sciences, Makerere University, Kampala, Uganda.
Joan N KalyangoClinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.
Jane Frances ZalwangoClinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.
Judith Amutuhaire SsemasaaziClinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.
Tom OkelloClinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.
Remmy BuhuguruClinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.
Sarah KiguliDepartment of Pediatrics and Child Health College of Health Sciences, Makerere University, Kampala, Uganda.
Aloysius G MubuukeDepartment of Radiology, School of Medicine, Makerere University, Kampala, Uganda.
Sam OnongeDepartment of Obstetrics and Gynecology, College of Health Sciences, Makerere University, Kampala, Uganda.
Makerere University · UG

Funding

Health Professions Education and training for strengthening the health system and services in UgandaR25TW011213 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI KIGULI, SARAH · 2018 to 2022
$3.4M
FIC NIH HHS R25 TW011213PEPFAR
6 · The paper itself

Abstract

backgroundGroup antenatal care (G-ANC), an alternative to focused ANC (F-ANC), involves grouping mothers by gestational and maternal age. In high-income countries, G-ANC has been associated with improved utilization of health care services like Prevention of Mother to Child Transmission (PMTCT) of HIV services. Some low-resource countries with poor utilization of health care services have piloted G-ANC. However, there is limited evidence of its efficiency. We, therefore, compared G-ANC versus F-ANC with regards to optimal utilization of PMTCT of HIV services and assessed associated factors thereof among adolescent mothers in eastern Uganda. We defined optimal utilization of PMTCT of HIV services as the adolescent being up to date with HIV counseling and testing. If found HIV negative, subsequent timely re-testing. If found HIV positive, initiation of antiretroviral therapy (ART) under option B plus for the mother. While for the infant, it entailed safe delivery, testing, feeding, and appropriate HIV chemotherapy.

methodsFrom February to April 2020, we conducted a cross-sectional study among 528 adolescent mothers in four sites in eastern Uganda. We assessed the optimal utilization of PMTCT of HIV services among adolescent mothers that had attended G-ANC versus F-ANC at the post-natal care or immunization clinics. We also assessed the factors associated with optimal utilization of PMTCT of HIV services among these mothers.

resultsOptimal utilization of PMTCT was higher among those in G-ANC than in F-ANC (74.7% vs 41.2, p-0.0162). There was a statistically significant association between having attended G-ANC and optimal utilization of PMTCT [PR = 1.080, 95%CI (1.067-1.093)]. Other factors independently associated with optimal utilization were; having a partner that tested for HIV [PR = 1.075, 95%CI (1.048-1.103)], trimester of first ANC visit: second trimester [PR = 0.929, 95%CI (0.902-0.957)] and third trimester [PR = 0.725, 95%CI (0.616-0.853)], and the health facility attended: Bugembe HCIV [PR = 1.126, 95%CI (1.113-1.139)] and Jinja regional referral hospital [PR = 0.851, 95%CI (0.841-0.861].

conclusionsAdolescent mothers under G-ANC had significantly higher optimal utilization of PMTCT of HIV services compared to those under F-ANC. We recommend that the Ministry of Health considers widely implementing G-ANC, especially for adolescent mothers.

Indexed as

HIV InfectionsPregnancy Complications, InfectiousAdolescentCross-Sectional StudiesFemaleHumansInfantInfectious Disease Transmission, VerticalPregnancyPrenatal CareUganda

Identifiers

PMID36318523
PMCPMC9624396
OpenAlexW4307832779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.