Evidence map›Paper›PMID 36318478›Full record

ArticleGlobal spine journal2024

Utilization of Machine Learning to Model Important Features of 30-day Readmissions following Surgery for Metastatic Spinal Column Tumors: The Influence of Frailty.

Aladine A Elsamadicy, Andrew B Koo, Benjamin C Reeves, James L Cross, Andrew Hersh, Astrid C Hengartner, Aditya V Karhade, Zach Pennington, Oluwaseun O Akinduro, Sheng-Fu Larry Lo and 4 more

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Aladine A ElsamadicyDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-7658-6461
Andrew B KooDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.
Benjamin C ReevesDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.
James L CrossDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.
Andrew HershDepartment of Neurosurgery, John Hopkins School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-1755-3974
Astrid C HengartnerDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0003-0887-6851
Aditya V KarhadeDepartment of Orthopedics, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-6026-4361
Zach PenningtonDepartment of Neurosurgery, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-8012-860X
Oluwaseun O AkinduroDepartment of Neurologic Surgery, Mayo Clinic, Jacksonville, FL, USA.
Sheng-Fu Larry LoDepartment of Neurosurgery, Zucker School of Medicine at Hofstra, Long Island Jewish Medical Center and North Shore University Hospital, Northwell Health, Manhasset, NY, USA.
Ziya L GokaslanDepartment of Neurosurgery, The Warren Alpert Medical School of Brown University, Providence, RI, USA.
John H ShinDepartment of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Ehud MendelDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.
Daniel M SciubbaDepartment of Neurosurgery, John Hopkins School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-7604-434X
Yale University · USHarvard University · USNorthwell Health · USBrown University · USJohns Hopkins University · USMayo Clinic in Arizona · USWinnMed · US

Funding

Short Term Research Training: Students in Health Professional SchoolsT35DK104689 · NIDDK · YALE UNIVERSITY · PI LLOYD G CANTLEY, Sarwat I Chaudhry · 2015 to 2026
$2.6M
NIDDK NIH HHS T35 DK104689
6 · The paper itself

Abstract

STUDY

designRetrospective cohort study.

objectiveThe aim of this study was to determine the relative importance and predicative power of the Hospital Frailty Risk Score (HFRS) on unplanned 30-day readmission after surgical intervention for metastatic spinal column tumors.

methodsAll adult patients undergoing surgery for metastatic spinal column tumor were identified in the Nationwide Readmission Database from the years 2016 to 2018. Patients were categorized into 3 cohorts based on the criteria of the HFRS: Low(<5), Intermediate(5-14.9), and High(≥ 15). Random Forest (RF) classification was used to construct predictive models for 30-day patient readmission. Model performance was examined using the area under the receiver operating curve (AUC), and the Mean Decrease Gini (MDG) metric was used to quantify and rank features by relative importance.

resultsThere were 4346 patients included. The proportion of patients who required any readmission were higher among the Intermediate and High frailty cohorts when compared to the Low frailty cohort (

conclusionOur study utilizes machine learning approaches and predictive modeling to identify frailty as a significant risk-factor that contributes to unplanned 30-day readmission after spine surgery for metastatic spinal column metastases.

Indexed as

30-day readmissionfrailtymachine learningmetastasesspinal column tumor

Identifiers

PMID36318478
PMCPMC11289550
OpenAlexW4307840499

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.