Evidence map›Paper›PMID 36318368›Full record

ArticlePulmonary therapy2022

Effectiveness and Treatment Compliance of Salmeterol-Fluticasone Easyhaler

Lilla Tamási, Anna Bartha, Aranka Ferencz, Mihály Tímár, Mikko Vahteristo, Aino Takala, Veronika Müller

Open access · goldAbstract read
In one paragraph

Article in Pulmonary therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Real-Life Effectiveness of Aclidinium/Formoterol on COPD Control: The REDACT Observational Study.International journal of chronic obstructive pulmonary disease · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Lilla TamásiDepartment of Pulmonology, Faculty of Medicine, Semmelweis University, Tömő utca 25-29, 1083, Budapest, Hungary. tamasi.lilla@med.semmelweis-univ.hu.ORCID http://orcid.org/0000-0003-3477-6125
Anna BarthaSiófok Hospital and Outpatient Clinic of Pulmonology, Siófok, Hungary.
Aranka FerenczFerenc Toldy Hospital and Outpatient Clinic of Pulmonology, Cegléd, Hungary.
Mihály TímárHungarian Army Medical Center, Budapest, Hungary.
Mikko VahteristoOrion Corporation, Espoo, Finland.
Aino TakalaOrion Corporation, Espoo, Finland.
Veronika MüllerDepartment of Pulmonology, Faculty of Medicine, Semmelweis University, Tömő utca 25-29, 1083, Budapest, Hungary.
Orion Corporation (Finland) · FISemmelweis University · HUToldy Ferenc Kórház · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFor inhalation therapies to be effective, it is crucial that patients manage inhaler use correctly in their everyday life and achieve treatment compliance. We investigated the effectiveness of the salmeterol-fluticasone propionate Easyhaler

methodsA prospective, open-label, multicenter, noninterventional, investigator-sponsored study was conducted in outpatient pneumonology centers. Eligible patients were aged ≥ 18 years with either a new diagnosis of asthma, COPD, or ACO, or whose disease was not controlled with preexisting medication. Data were collected at baseline and 12 + 4 weeks, including the asthma control test (ACT), COPD assessment test (CAT), spirometry parameters [including forced expiratory volume for 1 s (FEV

resultsFive hundred sixteen patients were recruited from 103 centers: 376 with asthma; 104 with COPD; and 36 with ACO. At week 12, there were significant improvements from baseline in both mean ACT score in patients with asthma (14.4 ± 4.2 versus 21.4 ± 2.8; P < 0.001) and mean CAT score in patients with COPD (24.0 ± 6.1 versus 16.0 ± 5.8; P < 0.001). Significant improvement was observed when the switch from the most frequently used previous inhalers was analyzed separately. Mean FEV

conclusionsTreatment with SF EH significantly improved patients' lung function parameters and disease control.

Indexed as

Clinical effectivenessDevice-metered dry powder inhalerLung functionObstructive lung diseasePatient-reported outcomesReal-world setting

Identifiers

PMID36318368
PMCPMC9628494
OpenAlexW4308040936

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.