ArticleRadiology2023
Longitudinal Monitoring of Microstructural Alterations in Cerebral Ischemia with in Vivo Diffusion-weighted MR Spectroscopy.
Registry-linked trialOpen access · greenAbstract read
In one paragraph
Article in Radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02833961 (DIFFUSION SPECTROSCOPY AND IMAGING IN ACUTE STROKE), which is not on this map. Cited by 7 papers.
0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Diffusion spectroscopy and imaging in acute stroke
Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Article
- Added Value of Sodium MR Imaging and Proton MR Spectroscopy to Conventional MR Imaging for a Better Characterization of the Ischemic Stroke: A Narrative Review.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Review
- Article
- ISMRM Clinical Focus Meeting 2023: "Imaging the Fire in the Brain".Journal of magnetic resonance imaging : JMRI · 2025Article
- Single-shot diffusion trace spectroscopic imaging using radial echo planar trajectories.Magnetic resonance in medicine · 2024Article
- Single-shot diffusion trace-weighted MR spectroscopy: Comparison with unipolar and bipolar diffusion-weighted point-resolved spectroscopy.NMR in biomedicine · 2024Article
- Neuroimmunometabolic alterations and severity of depressive symptoms in people with HIV: An exploratory diffusion-weighted MRS study.Brain and neuroscience advancesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Guglielmo Genovese *From the Paris Brain Institute (Institut du Cerveau-ICM), Center for Neuroimaging Research-CENIR, Hôpital Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, CS 21414, 75646 Paris Cedex 13, France (G.G., L.Y.C., S.L., F.B.); Hopital Pitié-Salpêtrière, ICM, Sorbonne Université, Inserm U 1127, CNRS UMR 7225, Paris, France (G.G., F.X.L., L.Y.C., S.L., F.B., C.R.); APHP-Urgences Cérébro-Vasculaires, Hôpital Pitié-Salpêtrière, Paris, France (B.D.F., C.R.); Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minn (G.G., M.M.); Paris Brain Institute's Data Analysis Core, Paris, France (F.X.L.); Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, Falmer, United Kingdom (I.R.); and STARE Team, iCRIN, Institut du Cerveau et de la Moelle Épinière, ICM, Paris, France (C.R.).ORCID 0000-0001-9409-0120
Belén Diaz-Fernandez *From the Paris Brain Institute (Institut du Cerveau-ICM), Center for Neuroimaging Research-CENIR, Hôpital Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, CS 21414, 75646 Paris Cedex 13, France (G.G., L.Y.C., S.L., F.B.); Hopital Pitié-Salpêtrière, ICM, Sorbonne Université, Inserm U 1127, CNRS UMR 7225, Paris, France (G.G., F.X.L., L.Y.C., S.L., F.B., C.R.); APHP-Urgences Cérébro-Vasculaires, Hôpital Pitié-Salpêtrière, Paris, France (B.D.F., C.R.); Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minn (G.G., M.M.); Paris Brain Institute's Data Analysis Core, Paris, France (F.X.L.); Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, Falmer, United Kingdom (I.R.); and STARE Team, iCRIN, Institut du Cerveau et de la Moelle Épinière, ICM, Paris, France (C.R.).ORCID 0000-0002-3731-2054
François-Xavier LejeuneFrom the Paris Brain Institute (Institut du Cerveau-ICM), Center for Neuroimaging Research-CENIR, Hôpital Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, CS 21414, 75646 Paris Cedex 13, France (G.G., L.Y.C., S.L., F.B.); Hopital Pitié-Salpêtrière, ICM, Sorbonne Université, Inserm U 1127, CNRS UMR 7225, Paris, France (G.G., F.X.L., L.Y.C., S.L., F.B., C.R.); APHP-Urgences Cérébro-Vasculaires, Hôpital Pitié-Salpêtrière, Paris, France (B.D.F., C.R.); Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minn (G.G., M.M.); Paris Brain Institute's Data Analysis Core, Paris, France (F.X.L.); Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, Falmer, United Kingdom (I.R.); and STARE Team, iCRIN, Institut du Cerveau et de la Moelle Épinière, ICM, Paris, France (C.R.).ORCID 0000-0002-6229-5364
Itamar RonenFrom the Paris Brain Institute (Institut du Cerveau-ICM), Center for Neuroimaging Research-CENIR, Hôpital Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, CS 21414, 75646 Paris Cedex 13, France (G.G., L.Y.C., S.L., F.B.); Hopital Pitié-Salpêtrière, ICM, Sorbonne Université, Inserm U 1127, CNRS UMR 7225, Paris, France (G.G., F.X.L., L.Y.C., S.L., F.B., C.R.); APHP-Urgences Cérébro-Vasculaires, Hôpital Pitié-Salpêtrière, Paris, France (B.D.F., C.R.); Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minn (G.G., M.M.); Paris Brain Institute's Data Analysis Core, Paris, France (F.X.L.); Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, Falmer, United Kingdom (I.R.); and STARE Team, iCRIN, Institut du Cerveau et de la Moelle Épinière, ICM, Paris, France (C.R.).
Małgorzata MarjańskaFrom the Paris Brain Institute (Institut du Cerveau-ICM), Center for Neuroimaging Research-CENIR, Hôpital Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, CS 21414, 75646 Paris Cedex 13, France (G.G., L.Y.C., S.L., F.B.); Hopital Pitié-Salpêtrière, ICM, Sorbonne Université, Inserm U 1127, CNRS UMR 7225, Paris, France (G.G., F.X.L., L.Y.C., S.L., F.B., C.R.); APHP-Urgences Cérébro-Vasculaires, Hôpital Pitié-Salpêtrière, Paris, France (B.D.F., C.R.); Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minn (G.G., M.M.); Paris Brain Institute's Data Analysis Core, Paris, France (F.X.L.); Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, Falmer, United Kingdom (I.R.); and STARE Team, iCRIN, Institut du Cerveau et de la Moelle Épinière, ICM, Paris, France (C.R.).ORCID 0000-0002-4727-2447
Lydia Yahia-CherifFrom the Paris Brain Institute (Institut du Cerveau-ICM), Center for Neuroimaging Research-CENIR, Hôpital Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, CS 21414, 75646 Paris Cedex 13, France (G.G., L.Y.C., S.L., F.B.); Hopital Pitié-Salpêtrière, ICM, Sorbonne Université, Inserm U 1127, CNRS UMR 7225, Paris, France (G.G., F.X.L., L.Y.C., S.L., F.B., C.R.); APHP-Urgences Cérébro-Vasculaires, Hôpital Pitié-Salpêtrière, Paris, France (B.D.F., C.R.); Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minn (G.G., M.M.); Paris Brain Institute's Data Analysis Core, Paris, France (F.X.L.); Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, Falmer, United Kingdom (I.R.); and STARE Team, iCRIN, Institut du Cerveau et de la Moelle Épinière, ICM, Paris, France (C.R.).ORCID 0000-0002-7107-7588
Stéphane LehéricyFrom the Paris Brain Institute (Institut du Cerveau-ICM), Center for Neuroimaging Research-CENIR, Hôpital Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, CS 21414, 75646 Paris Cedex 13, France (G.G., L.Y.C., S.L., F.B.); Hopital Pitié-Salpêtrière, ICM, Sorbonne Université, Inserm U 1127, CNRS UMR 7225, Paris, France (G.G., F.X.L., L.Y.C., S.L., F.B., C.R.); APHP-Urgences Cérébro-Vasculaires, Hôpital Pitié-Salpêtrière, Paris, France (B.D.F., C.R.); Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minn (G.G., M.M.); Paris Brain Institute's Data Analysis Core, Paris, France (F.X.L.); Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, Falmer, United Kingdom (I.R.); and STARE Team, iCRIN, Institut du Cerveau et de la Moelle Épinière, ICM, Paris, France (C.R.).ORCID 0000-0002-5802-3518
Francesca Branzoli *From the Paris Brain Institute (Institut du Cerveau-ICM), Center for Neuroimaging Research-CENIR, Hôpital Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, CS 21414, 75646 Paris Cedex 13, France (G.G., L.Y.C., S.L., F.B.); Hopital Pitié-Salpêtrière, ICM, Sorbonne Université, Inserm U 1127, CNRS UMR 7225, Paris, France (G.G., F.X.L., L.Y.C., S.L., F.B., C.R.); APHP-Urgences Cérébro-Vasculaires, Hôpital Pitié-Salpêtrière, Paris, France (B.D.F., C.R.); Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minn (G.G., M.M.); Paris Brain Institute's Data Analysis Core, Paris, France (F.X.L.); Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, Falmer, United Kingdom (I.R.); and STARE Team, iCRIN, Institut du Cerveau et de la Moelle Épinière, ICM, Paris, France (C.R.).ORCID 0000-0001-9792-0492
Charlotte Rosso *From the Paris Brain Institute (Institut du Cerveau-ICM), Center for Neuroimaging Research-CENIR, Hôpital Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, CS 21414, 75646 Paris Cedex 13, France (G.G., L.Y.C., S.L., F.B.); Hopital Pitié-Salpêtrière, ICM, Sorbonne Université, Inserm U 1127, CNRS UMR 7225, Paris, France (G.G., F.X.L., L.Y.C., S.L., F.B., C.R.); APHP-Urgences Cérébro-Vasculaires, Hôpital Pitié-Salpêtrière, Paris, France (B.D.F., C.R.); Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minn (G.G., M.M.); Paris Brain Institute's Data Analysis Core, Paris, France (F.X.L.); Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, Falmer, United Kingdom (I.R.); and STARE Team, iCRIN, Institut du Cerveau et de la Moelle Épinière, ICM, Paris, France (C.R.).
Centre National de la Recherche Scientifique · FR
Funding
TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger, KAMIL UGURBIL · 2019 to 2026
$11.7MInstitutional Center Cores for Advanced NeuroimagingP30NS076408 · NINDS · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2020
$4.2MNIBIB NIH HHS P41 EB027061NINDS NIH HHS P30 NS076408
Abstract
Background The time course of cellular damage after acute ischemic stroke (IS) is currently not well known, and specific noninvasive markers of microstructural alterations linked to inflammation are lacking, which hinders the monitoring of anti-inflammatory treatment. Purpose To evaluate the temporal pattern of neuronal and glial microstructural changes after stroke using in vivo single-voxel diffusion-weighted MR spectroscopy. Materials and Methods In this prospective longitudinal study, participants with IS and healthy volunteers (HVs) underwent MRI at 3.0 T. In participants with IS, apparent diffusion coefficients (ADCs) and concentrations of total
Indexed as
Brain IschemiaIschemic StrokeCholineCreatineFemaleHumansLongitudinal StudiesMagnetic Resonance SpectroscopyMiddle AgedProspective StudiesReceptors, Antigen, T-CellCholineCreatineReceptors, Antigen, T-Cell
Identifiers
What OpenQuestion holds
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Registered trials
NCT02833961ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.