Evidence map›Paper›PMID 36317998›Full record

Observational studyActa medica academica2022

Evaluation of SARS-CoV-2 Antibody Response Post Third Dose COVID-19 mRNA Vaccination at Universitas Indonesia Hospital.

Rakhmad Hidayat, Alyssa Putri Mustika, Fhathia Avisha, Zlatikha Djuliannisaa, Dinisa Diah Winari, Ria Amiliah Putri, Heydi Marizky Lisman, Vandra Davin, Gemia Clarisa Fathi, Alvina Widhani and 6 more

Open access · diamondAbstract readObservational Study
In one paragraph

Observational study in Acta medica academica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Rakhmad HidayatFaculty of Medicine Universitas Indonesia, Indonesia; Dr. Cipto Mangunkusumo Hospital, Indonesia; Universitas Indonesia Hospital, Indonesia. rhidayat.md@gmail.com, rhidayat81@gmail.ui.ac.id.
Alyssa Putri MustikaFaculty of Medicine Universitas Indonesia, Indonesia; Dr. Cipto Mangunkusumo Hospital, Indonesia; Universitas Indonesia Hospital, Indonesia.
Fhathia AvishaUniversitas Indonesia Hospital, Indonesia.
Zlatikha DjuliannisaaFaculty of Medicine Universitas Indonesia, Indonesia; Dr. Cipto Mangunkusumo Hospital, Indonesia.
Dinisa Diah WinariUniversitas Indonesia Hospital, Indonesia.
Ria Amiliah PutriUniversitas Indonesia Hospital, Indonesia.
Heydi Marizky LismanUniversitas Indonesia Hospital, Indonesia.
Vandra DavinUniversitas Indonesia Hospital, Indonesia.
Gemia Clarisa FathiUniversitas Indonesia Hospital, Indonesia.
Alvina WidhaniFaculty of Medicine Universitas Indonesia, Indonesia; Dr. Cipto Mangunkusumo Hospital, Indonesia; Universitas Indonesia Hospital, Indonesia.
Muhammad Hafiz AiniFaculty of Medicine Universitas Indonesia, Indonesia; Dr. Cipto Mangunkusumo Hospital, Indonesia; Universitas Indonesia Hospital, Indonesia.
Yudhistira YudhistiraUniversitas Indonesia Hospital, Indonesia.
Siti AzizahFaculty of Medicine Universitas Indonesia, Indonesia; Universitas Indonesia Hospital, Indonesia.
Meilisa RahmadaniUniversitas Indonesia Hospital, Indonesia.
Novita Dwi IstantiUniversitas Indonesia Hospital, Indonesia.
Astuti GiantiniFaculty of Medicine Universitas Indonesia, Indonesia; Dr. Cipto Mangunkusumo Hospital, Indonesia; Universitas Indonesia Hospital, Indonesia.
University of Indonesia · IDRumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe longevity of vaccine effectiveness and antibody titer after the Moderna mRNA COVID-19 vaccination booster in healthcare workers in Indonesia is not known. MATERIALS AND

methodsWe performed a prospective observational study of healthcare workers at the Universitas Indonesia Hospital after Moderna mRNA COVID-19 booster vaccination. An Immunology Analyzer with Chemiluminescence Immunoassay (CLIA) test was used to examine Anti SARS-CoV-2 S-RBD levels. Antibody levels were classified into two systems (3 categories, and 2 categories).

resultsThere were 31 male subjects (75.6%), 33 subjects (80.5%) aged 25-39 years, 17 subjects (41.5%) with overweight BMI, 35 subjects (85.4%) without comorbidities, and 29 subjects without previous history of COVID-19 infection (70.7%) who had antibody titer >1000 AU/ml. There were 27 subjects (65.9%) who had a booster shot ≥6 months after the second vaccination with antibody titer >1000 AU/ml. In this study, there was no significant correlation between antibody titer with factors such as gender, age, BMI, comorbidities, history of COVID-19 infection and time between the 2nd vaccination and booster vaccination.

conclusionThere is no significant correlation between antibody titer with factors such as gender, age, BMI, comorbidities, history of COVID-19 infection and time between the 2nd vaccination and booster vaccination.

Indexed as

Antibody FormationCOVID-19Antibodies, ViralCOVID-19 VaccinesHospitalsHumansIndonesiaMaleRNA, MessengerSARS-CoV-2VaccinationAntibodies, ViralCOVID-19 VaccinesRNA, MessengerCOVID-19SARS-CoV-2Vaccine

Identifiers

PMID36317998
PMCPMC9982858
OpenAlexW4307002397

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.