Evidence map›Paper›PMID 36317921›Full record

ArticleJournal of bacteriology2022

PBP1A Directly Interacts with the Divisome Complex to Promote Septal Peptidoglycan Synthesis in Acinetobacter baumannii.

Katie N Kang, Joseph M Boll

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. LPS in gram-negative bacterial growth and physiology: outside but fully integrated.Microbiology and molecular biology reviews : MMBR · 2026
    Review
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  5. Journal of bacteriology · 2025
    Article
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  12. AnBiochemistry and biophysics reports · 2024
    Article
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  17. Transcriptome reveals the role of theFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Katie N KangDepartment of Biology, University of Texas Arlington, Arlington, Texas, USA.ORCID 0000-0003-3026-5360
Joseph M BollDepartment of Biology, University of Texas Arlington, Arlington, Texas, USA.ORCID 0000-0003-1412-9780
The University of Texas at Arlington · US

Funding

Mechanistic basis of how LD-transpeptidases protect against outer membranedefectsR01AI168159 · NIAID · UNIVERSITY OF TEXAS DALLAS · PI Joseph Michael Boll · 2022 to 2026
$2.3M
Reinforcing the barrier: Understanding how cell envelope modifications promote intrinsic antimicrobial tolerance and resistance in Acinetobacter baumanniiR35GM143053 · NIGMS · UNIVERSITY OF TEXAS DALLAS · PI BOLL, JOSEPH MICHAEL · 2021 to 2025
$1.9M
NIAID NIH HHS R01 AI168159NIGMS NIH HHS R35 GM143053
6 · The paper itself

Abstract

The class A penicillin-binding proteins (aPBPs), PBP1A and PBP1B, are major peptidoglycan synthases that synthesize more than half of the peptidoglycan per generation in Escherichia coli. Whereas aPBPs have distinct roles in peptidoglycan biosynthesis during growth (i.e., elongation and division), they are semiredundant; disruption of either is rescued by the other to maintain envelope homeostasis and promote proper growth. Acinetobacter baumannii is a nosocomial pathogen that has a high propensity to overcome antimicrobial treatment. A. baumannii contains both PBP1A and PBP1B (encoded by

Indexed as

Acinetobacter baumanniiCross InfectionEscherichia coli ProteinsPeptidoglycan GlycosyltransferaseAnti-Bacterial AgentsEscherichia coliHumansPenicillin-Binding ProteinsPeptidoglycanAnti-Bacterial AgentsEscherichia coli ProteinsPBP5 protein, E coliPenicillin-Binding ProteinsPeptidoglycanPeptidoglycan GlycosyltransferasedivisionelongationGram-negativeGram-negative bacteriapenicillin-binding proteinpeptidoglycanseptation

Identifiers

PMID36317921
PMCPMC9765026
OpenAlexW4308188084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.