Evidence map›Paper›PMID 36317478›Full record

ArticlePediatrics2022

Six-Month Outcomes of Infants Born to People With SARS-CoV-2 in Pregnancy.

Lucas Gosdin, Bailey Wallace, Tatiana M Lanzieri, Emily O'Malley Olsen, Elizabeth L Lewis, Daniel J Chang, Salma Khuwaja, Sarah Chicchelly, Kristen D Ojo, Mamie Lush and 11 more

Open access · greenAbstract read
In one paragraph

Article in Pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Critical care among newborns with and without a COVID-19 diagnosis, May 2020-February 2022.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 10 institutions in 3 countries.

Lucas GosdinCOVID-19 Emergency Response.
Bailey WallaceCOVID-19 Emergency Response.
Tatiana M LanzieriCOVID-19 Emergency Response.
Emily O'Malley OlsenCOVID-19 Emergency Response.
Elizabeth L LewisCOVID-19 Emergency Response.
Daniel J ChangCOVID-19 Emergency Response.
Salma KhuwajaHouston Health Department, Houston, Texas.
Sarah ChicchellyKansas Department of Health and Environment, Topeka, Kansas.
Kristen D OjoMinnesota Department of Health, Saint Paul, Minnesota.
Mamie LushNebraska Department of Health and Human Services, Lincoln, Nebraska.
Daniel HeitnerNew Jersey Department of Health, Trenton, New Jersey.
Nicole D LongcoreNew York State Department of Health, Albany, New York.
Camille Delgado-LópezPuerto Rico Department of Health, San Juan, Puerto Rico.
Brian K HumphriesSouth Carolina Department of Health and Environmental Control Columbia, South Carolina.
Lindsey SizemoreTennessee Department of Health, Nashville, Tennessee.
Deborah MbothaWashington State Department of Health, Olympia, Washington.
Aron J HallCOVID-19 Emergency Response.
Sascha EllingtonCOVID-19 Emergency Response.
Suzanne M GilboaCOVID-19 Emergency Response.
Van T TongCOVID-19 Emergency Response.
Kate WoodworthCOVID-19 Emergency Response.
Computer Emergency Response Team · FRKansas Department of Health and Environment · USMinnesota Department of Health · USNebraska Department of Health and Human Services · USNew Jersey Department of Health · USNew York State Department of Health · USPuerto Rico Department of Health · PRSouth Carolina Department of Health and Environmental Control · USTennessee Department of Health · USWashington State Department of Health · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectivesTo assess the 6-month incidence of laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, postnatal care, hospitalization, and mortality among infants born to people with laboratory-confirmed SARS-CoV-2 infection during pregnancy by timing of maternal infection.

methodsUsing a cohort of liveborn infants from pregnancies with SARS-CoV-2 infections in the year 2020 from 10 United States jurisdictions in the Surveillance for Emerging Threats to Mother and Babies Network, we describe weighted estimates of infant outcomes from birth through 6 months of age from electronic health and laboratory records.

resultsOf 6601 exposed infants with laboratory information through 6 months of age, 1.0% (95% confidence interval: 0.8-1.1) tested positive, 19.1% (17.5-20.6) tested negative, and 80.0% (78.4-81.6) were not known to be tested for SARS-CoV-2. Among those ≤14 days of age, SARS-CoV-2 infection occurred only with maternal infection ≤14 days before delivery. Of 3967 infants with medical record abstraction, breastmilk feeding initiation was lower when maternal infection occurred ≤14 days before delivery compared with >14 days (77.6% [72.5-82.6] versus 88.3% [84.7-92.0]). Six-month all-cause hospitalization was 4.1% (2.0-6.2). All-cause mortality was higher among infants born to people with infection ≤14 days (1.0% [0.4-1.6]) than >14 days (0.3% [0.1-0.5]) before delivery.

conclusionsResults are reassuring, with low incidences of most health outcomes examined. Incidence of infant SARS-CoV-2, breastmilk feeding initiation, and all-cause mortality differed by timing of maternal infection. Strategies to prevent infections and support pregnant people with coronavirus disease 2019 may improve infant outcomes.

Indexed as

COVID-19Pregnancy Complications, InfectiousCOVID-19 TestingFemaleHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalPregnancyPregnancy OutcomeSARS-CoV-2United States

Identifiers

PMID36317478
PMCPMC9761394
OpenAlexW4307835427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.