Evidence map›Paper›PMID 36317360›Full record

ArticleCancer research and treatment2023

The Additive Impact of Transbronchial Cryobiopsy Using a 1.1-mm Diameter Cryoprobe on Conventional Biopsy for Peripheral Lung Nodules.

Soo Han Kim, Jeongha Mok, Eun-Jung Jo, Mi-Hyun Kim, Kwangha Lee, Ki Uk Kim, Hye-Kyung Park, Min Ki Lee, Jung Seop Eom

Open access · diamondAbstract read
In one paragraph

Article in Cancer research and treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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  18. Advanced Bronchoscopic Diagnostic Techniques in Lung Cancer.Tuberculosis and respiratory diseases · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Soo Han KimDepartment of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Jeongha MokDepartment of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Eun-Jung JoDepartment of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Mi-Hyun KimDepartment of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Kwangha LeeDepartment of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Ki Uk KimDepartment of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Hye-Kyung ParkDepartment of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Min Ki LeeDepartment of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Jung Seop EomDepartment of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Pusan National University · KRPusan National University Hospital · KR

Funding

Pusan National University Hospital
6 · The paper itself

Abstract

purposeThe diagnostic yield of transbronchial biopsy (TBB) using radial probe endobronchial ultrasound (RP-EBUS) is 71%, which is lower than that of transthoracic needle biopsy. We investigated the performance and safety of sequential transbronchial cryobiopsy (TBC) using a novel 1.1-mm diameter cryoprobe, after conventional TBB using RP-EBUS for the diagnosis of peripheral lung lesions (PLLs). Materials and Methods: From April 2021 to November 2021, 110 patients who underwent bronchoscopy using RP-EBUS for the diagnosis of PLL ≤ 30 mm were retrospectively included in our study. All records were followed until June 2022.

resultsThe overall diagnostic yield of combined TBB and TBC was 79.1%, which was higher than 60.9% of TBB alone (p=0.005). The diagnostic yield of sequential TBC was 65.5%, which increased the overall diagnostic yield by 18.2%. The surface area of tissues by TBC (mean area, 18.5 mm2) was significantly larger than those of TBB by 1.5-mm forceps (3.4 mm2, p < 0.001) and 1.9-mm forceps (3.7 mm2, p=0.011). In the multivariate analysis, PLLs with the longest diameter of ≤ 22 mm were found to be related to additional diagnostic benefits from sequential TBC (odds ratio, 3.51; 95% confidence interval, 1.043 to 11.775; p=0.042). Complications were found in 10.5% of the patients: pneumothorax (1.0%), infection (1.0%), and significant bleeding (8.6%). None of the patients developed any life-threatening complications.

conclusionSequential TBC with a 1.1-mm cryoprobe improved the performance of conventional TBB using RP-EBUS without serious complications.

Indexed as

Lung NeoplasmsBiopsyBronchoscopyHumansLungRetrospective StudiesBronchoscopyDiagnosisLung neoplasmsUltrasonography

Identifiers

PMID36317360
PMCPMC10101800
OpenAlexW4307846375

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.